GEN1

Gene Symbol GEN1
Entrez Gene 348654
Alt Symbol Gen
Species Human
Gene Type protein-coding
Description GEN1 Holliday junction 5' flap endonuclease
Other Description Gen endonuclease homolog 1|Gen homolog 1, endonuclease|Holliday junction resolvase|flap endonuclease GEN homolog 1
Swissprots Q17RS7 Q6ZN37 Q17RS9
Accessions EAX00865 Q17RS7 AK025489 AK093631 AK098188 BAC05254 AK131387 BAD18538 BC035863 BC038243 BC117204 AAI17205 BC117206 AAI17207 BX490061 CR936783 HQ258680 ADR83431 XM_005262613 XP_005262670 XM_006712005 XP_006712068 XM_011532820 XP_011531122 XM_011532821 XP_011531123 XM_011532822 XP_011531124 NM_001130009 NP_001123481 NM_182625 NP_872431
Function Endonuclease which resolves Holliday junctions by the introduction of symmetrically related cuts across the junction point, to produce nicked duplex products in which the nicks can be readily ligated. Four-way DNA intermediates, also known as Holliday junctions, are formed during homologous recombination and DNA repair, and their resolution is necessary for proper chromosome segregation. {ECO:0000269|PubMed:19020614}.
Subcellular Location Nucleus {ECO:0000250}.

GEN1 overexpression lysate - LY403642 from Acris Antibodies

Category Cell Lysate
Prices $480.00
Sizes 100 µg

GEN1 overexpression lysate - LY427099 from Acris Antibodies

Category Cell Lysate
Prices $480.00
Sizes 100 µg

GEN1 293 Cell Lysate - 403140 from ABBIOTEC

Category Cell Lysate
Prices $672.00
Sizes 100 µg
Species Drosophila

GEN1 Overexpression Lysate (Native) - NBL1-11042 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: GEN1 Overexpression Lysate (Adult Normal) [NBL1-11042] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GEN1.

GEN1 Over-expression Lysate Product - GWB-83840D from Genway Biotech

Category Cell Lysate
Prices $756.00
Sizes 100 µg
Species Human

GEN1 Overexpression Lysate (Native) - NBP2-09495 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: GEN1 Overexpression Lysate (Adult Normal) [NBP2-09495] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GEN1.

Panoply™ Human GEN1 Knockdown Stable Cell Line - CSC-DC006210 from Creative biogene

Category Cell Line
Species Human
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