GEN1

Gene Symbol GEN1
Entrez Gene 348654
Alt Symbol Gen
Species Human
Gene Type protein-coding
Description GEN1 Holliday junction 5' flap endonuclease
Other Description Gen endonuclease homolog 1|Gen homolog 1, endonuclease|Holliday junction resolvase|flap endonuclease GEN homolog 1
Swissprots Q17RS7 Q6ZN37 Q17RS9
Accessions EAX00865 Q17RS7 AK025489 AK093631 AK098188 BAC05254 AK131387 BAD18538 BC035863 BC038243 BC117204 AAI17205 BC117206 AAI17207 BX490061 CR936783 HQ258680 ADR83431 XM_005262613 XP_005262670 XM_006712005 XP_006712068 XM_011532820 XP_011531122 XM_011532821 XP_011531123 XM_011532822 XP_011531124 NM_001130009 NP_001123481 NM_182625 NP_872431
Function Endonuclease which resolves Holliday junctions by the introduction of symmetrically related cuts across the junction point, to produce nicked duplex products in which the nicks can be readily ligated. Four-way DNA intermediates, also known as Holliday junctions, are formed during homologous recombination and DNA repair, and their resolution is necessary for proper chromosome segregation. {ECO:0000269|PubMed:19020614}.
Subcellular Location Nucleus {ECO:0000250}.

GEN1 CRISPR/Cas9 KO Plasmid (h) - sc-410437 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GEN1 HDR Plasmid (h) - sc-410437-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GEN1 Double Nickase Plasmid (h) - sc-410437-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GEN1 Double Nickase Plasmid (h2) - sc-410437-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GEN1 CRISPR Activation Plasmid (h) - sc-410437-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GEN1 CRISPR Activation Plasmid (h2) - sc-410437-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GEN1 Lentiviral Activation Particles (h) - sc-410437-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GEN1 Lentiviral Activation Particles (h2) - sc-410437-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GEN1 siRNA (h) - sc-94802 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GEN1 shRNA Plasmid (h) - sc-94802-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GEN1 shRNA (h) Lentiviral Particles - sc-94802-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GEN1 RNAi - H00348654-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU032181 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9235 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit - CKOZFN1465 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9235 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1465 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GEN1 siRNA (Human) - CRJ7538 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GEN1 - MBS8222493 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GEN1 (NM_182625.3) - SHH300522 from Creative biogene

Category siRNA
Species Reactivities Human

Human GEN1 siRNA - orb278039 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GEN1 shRNA Plasmid (Human) - CHJ7538 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GEN1 miRNA 3'UTR clone - MiUTR4H-TG03778 from Creative biogene

Species Reactivities Human
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