GEN1

Gene Symbol	GEN1
Entrez Gene	348654
Alt Symbol	Gen
Species	Human
Gene Type	protein-coding
Description	GEN1 Holliday junction 5' flap endonuclease
Other Description	Gen endonuclease homolog 1|Gen homolog 1, endonuclease|Holliday junction resolvase|flap endonuclease GEN homolog 1
Swissprots	Q17RS7 Q6ZN37 Q17RS9
Accessions	EAX00865 Q17RS7 AK025489 AK093631 AK098188 BAC05254 AK131387 BAD18538 BC035863 BC038243 BC117204 AAI17205 BC117206 AAI17207 BX490061 CR936783 HQ258680 ADR83431 XM_005262613 XP_005262670 XM_006712005 XP_006712068 XM_011532820 XP_011531122 XM_011532821 XP_011531123 XM_011532822 XP_011531124 NM_001130009 NP_001123481 NM_182625 NP_872431
Function	Endonuclease which resolves Holliday junctions by the introduction of symmetrically related cuts across the junction point, to produce nicked duplex products in which the nicks can be readily ligated. Four-way DNA intermediates, also known as Holliday junctions, are formed during homologous recombination and DNA repair, and their resolution is necessary for proper chromosome segregation. {ECO:0000269|PubMed:19020614}.
Subcellular Location	Nucleus {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GEN1 Antibody Blocking Peptide - LS-E10162 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GEN1-Antibody-N-term-Blocking-Peptide - BP9493a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Flap endonuclease GEN homolog 1(GEN1) ,partial - CSB-YP624193HU CSB-EP624193HU CSB-BP624193HU CSB-MP624193HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

GEN1 Peptide, Human - M34GP06210H from Creative Peptides Category Peptide Source Synthetic. Species Human

Flap endonuclease GEN homolog 1 (GEN1), partial, Recombinant Protein - MBS1364150 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

GEN1 Recombinant Protein Antigen - NBP2-30783PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

GEN1 Recombinant Protein Antigen - NBP2-30836PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Holliday junction resolvase (FPV187), Recombinant Protein - MBS1425200 from MyBioSource Category Protein Prices $900.00, $900.00, $1,120.00, $1,120.00, $1,320.00, $1,320.00, $1,775.00, $1,775.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Holliday junction resolvase (MVA133R, ACAM3000_MVA_133), Recombinant Protein - MBS1206765 from MyBioSource Category Protein Prices $935.00, $935.00, $1,155.00, $1,155.00, $1,395.00, $1,395.00, $1,850.00, $1,850.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

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