AKAP10

Gene Symbol AKAP10
Entrez Gene 11216
Alt Symbol AKAP-10, D-AKAP-2, D-AKAP2, PRKA10
Species Human
Gene Type protein-coding
Description A kinase (PRKA) anchor protein 10
Other Description A-kinase anchor protein 10, mitochondrial|dual specificity A kinase-anchoring protein 2|mitochondrial A kinase PPKA anchor protein 10|protein kinase A anchoring protein 10
Swissprots Q96AJ7 B2R650 O43572
Accessions EAW50913 O43572 AF037439 AAB92260 AK295180 BAH12002 AK308297 AK312438 BAG35347 BC017055 AAH17055 BC111518 BP229845 DQ270159 ABB76684 DQ891477 ABM82403 DQ894666 ABM85592 U00957 XM_006721431 XP_006721494 XM_006721432 XP_006721495 XR_243536 XR_933969 XR_933970 NM_007202 NP_009133
Function Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity). {ECO:0000250}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:11248059}. Membrane {ECO:0000269|PubMed:11248059}. Cytoplasm {ECO:0000269|PubMed:11248059}. Note=Predominantly mitochondrial but also membrane associated and cytoplasmic.

AKAP 10 CRISPR/Cas9 KO Plasmid (h) - sc-409815 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AKAP 10 HDR Plasmid (h) - sc-409815-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AKAP 10 Double Nickase Plasmid (h) - sc-409815-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AKAP 10 Double Nickase Plasmid (h2) - sc-409815-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AKAP 10 CRISPR Activation Plasmid (h) - sc-409815-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AKAP 10 CRISPR Activation Plasmid (h2) - sc-409815-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AKAP 10 Lentiviral Activation Particles (h) - sc-409815-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AKAP 10 Lentiviral Activation Particles (h2) - sc-409815-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AKAP 10 siRNA (h) - sc-93998 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AKAP 10 shRNA Plasmid (h) - sc-93998-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AKAP 10 shRNA (h) Lentiviral Particles - sc-93998-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AKAP10 RNAi - H00011216-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: AKAP10 RNAi [H00011216-R01V] - Analysis of AKAP10 over-expressed 293 cell line. Lane 2 cotransfected with AKAP10 Validated Chimera RNAi Lane 1 non-transfected control. Blot probed with H00011216-M04. GAPDH (36.1 kDa) used as loading control.

AKAP10 RNAi - H00011216-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU022291 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3002 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3002 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

AKAP10 siRNA (Human) - CRH7685 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AKAP10 - MBS8204960 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Akap10 (NM_007202.3) - SHH234174 from Creative biogene

Category siRNA
Species Reactivities Human

AKAP10 shRNA Plasmid (Human) - CHH7685 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AKAP10 miRNA 3'UTR clone - MiUTR3H-07016 from Creative biogene

Species Reactivities Human
Search more