AKAP10

Gene Symbol AKAP10
Entrez Gene 11216
Alt Symbol AKAP-10, D-AKAP-2, D-AKAP2, PRKA10
Species Human
Gene Type protein-coding
Description A kinase (PRKA) anchor protein 10
Other Description A-kinase anchor protein 10, mitochondrial|dual specificity A kinase-anchoring protein 2|mitochondrial A kinase PPKA anchor protein 10|protein kinase A anchoring protein 10
Swissprots Q96AJ7 B2R650 O43572
Accessions EAW50913 O43572 AF037439 AAB92260 AK295180 BAH12002 AK308297 AK312438 BAG35347 BC017055 AAH17055 BC111518 BP229845 DQ270159 ABB76684 DQ891477 ABM82403 DQ894666 ABM85592 U00957 XM_006721431 XP_006721494 XM_006721432 XP_006721495 XR_243536 XR_933969 XR_933970 NM_007202 NP_009133
Function Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity). {ECO:0000250}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:11248059}. Membrane {ECO:0000269|PubMed:11248059}. Cytoplasm {ECO:0000269|PubMed:11248059}. Note=Predominantly mitochondrial but also membrane associated and cytoplasmic.

AKAP 10 (A-7) - sc-166220 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AKAP 10 (A-7): sc-166220. Western blot analysis of AKAP 10 expression in non-transfected: sc-117752 (A) and human AKAP 10 transfected: sc-113119 (B) 293T whole cell lysates.

AKAP 10 (C-8) - sc-271074 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AKAP 10 (C-8): sc-271074. Western blot analysis of AKAP 10 expression in RAW 264.7 (A), NIH/3T3 (B) and KNRK (C) whole cell lysates.

AKAP 10 (E-7) - sc-166192 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AKAP 10 (E-7): sc-166192. Western blot analysis of AKAP 10 expression in non-transfected: sc-117752 (A) and human AKAP 10 transfected: sc-113119 (B) 293T whole cell lysates.

AKAP 10 (H-155) - sc-98755 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
AKAP 10 (H-155): sc-98755. Western blot analysis of AKAP 10 expression in RAW 264.7 whole cell lysate.

AKAP 10 (K-13) - sc-109187 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AKAP 10 (K-13): sc-109187. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in tubules.

AKAP 10 (N-13) - sc-109188 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

AKAP 10 (T-14) - sc-109189 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

AKAP 10 (51) - sc-136512 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AKAP 10 (51): sc-136512. Western blot analysis of AKAP 10 expression in Jurkat whole cell lysate.

Anti-AKAP10 antibody - ab97354 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-AKAP10 antibody (ab97354) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

Anti-AKAP10 antibody - ab97684 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-AKAP10 antibody (ab97684) at 1 µg/ml + Rat brain lysates at 35 µg

Anti-AKAP10 antibody - ab65038 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-AKAP10 antibody (ab65038) at 1/500 dilutionLane 1 : mouse brain cell extractLane 2 : mouse brain cell extract with immunising peptide at 10 µgLysates/proteins at 5 µg per lane.

Anti-AKAP10 antibody - ab168486 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-AKAP10 antibody (ab168486) at 1/500 dilutionLane 1 : Lysate from 293T cells transfected with AKAP10Lane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-AKAP10 Antibody (aa650-662) - LS-C54470 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-AKAP10 Antibody (aa28-40) - LS-C54469 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (1 ug/ml) staining of Rat Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-AKAP10 Antibody (Arg27) - LS-C191922 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-AKAP10 Antibody (aa600-662) - LS-C185809 from LifeSpan Bioscience

Prices $245.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded OVCAR3 using AKAP10 antibody at 1:100 dilution.

Anti-AKAP10 Antibody (clone 8C10) - LS-C133683 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 8C10
Immunoperoxidase of monoclonal antibody to AKAP10 on formalin-fixed paraffin-embedded human testis. [antibody concentration 0.5 ug/ml]

Anti-AKAP10 Antibody (aa10-59) - LS-C118683 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from mouse brain cells, using AKAP10 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-AKAP10 Antibody (aa575-624) - LS-C115983 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
AKAP10 antibody LS-C115983 Western blot of RPMI-8226 cell lysate.

AKAP10 Antibody (8C10) - H00011216-M04 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 8C10
Western Blot: AKAP10 Antibody (8C10) [H00011216-M04] - Analysis of AKAP10 expression in Raw 264.7.

AKAP10 Antibody - NBP1-31483 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

AKAP10 Antibody - NBP1-85314 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: AKAP10 Antibody [NBP1-85314] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

AKAP10 Antibody - NBP1-56509 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

AKAP10 Antibody - NB100-94882 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: AKAP10 Antibody [NB100-94882] - Analysis of AKAP10 using this antibody at 1 ug/ml in Rat Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

AKAP10 Antibody - H00011216-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: AKAP10 Antibody [H00011216-B01] - analysis of AKAP10 expression in transfected 293T cell line by AKAP10 MaxPab polyclonal antibody (B01). Lane 1: AKAP10 transfected lysate (73.80 KDa). Lane 2: Non-transfected lysate.
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