NFE2L2

Gene Symbol	NFE2L2
Entrez Gene	4780
Alt Symbol	NRF2
Species	Human
Gene Type	protein-coding
Description	nuclear factor, erythroid 2-like 2
Other Description	HEBP1|NF-E2-related factor 2|NFE2-related factor 2|nuclear factor (erythroid-derived 2)-like 2|nuclear factor erythroid 2-related factor 2|nuclear factor erythroid-derived 2-like 2|nuclear factor, erythroid derived 2, like 2
Swissprots	Q59HH2 B4E338 E9PGJ7 B2RBU2 Q96F71 Q53RW6 Q16236
Accessions	AAY14710 EAX11061 EAX11062 Q16236 AB208786 BAD92023 AF323119 AAK01657 AK297838 BAG60172 AK304555 BAG65350 AK310656 AK310841 AK311395 AK311688 AK314816 BAG37339 AK316148 BAH14519 AW471118 BC011558 AAH11558 BX649047 BX649071 CV575212 DA436387 DC314553 EU446639 ABZ92168 EU831991 ACE87432 EU832084 ACE86746 EU832824 ACE87835 GQ129228 ACT64362 HM446346 ADK56055 S74017 AAB32188 NM_001145412 NP_001138884 NM_001145413 NP_001138885 NM_006164 NP_006155
Function	Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region. {ECO:0000269|PubMed:11035812}.
Subcellular Location	Cytoplasm, cytosol. Nucleus. Note=Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents.
Tissue Specificity	Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle.
Top Pathways	Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Nrf2 full length protein - ab132356 from Abcam Category Protein Source Wheat germ Species Human

Human Nrf2 full length protein - ab202153 from Abcam Category Protein Source E. coli Species Human

Human Nrf2 peptide - ab71889 from Abcam Category Peptide

Human Nrf2 protein fragment - ab114160 from Abcam Category Protein Source Wheat germ Species Human

Human Nrf2 protein fragment - ab152571 from Abcam Category Protein Source Wheat germ Species Human

Nrf2 (phospho S40) peptide - ab133404 from Abcam Category Peptide

Nrf2 peptide - ab167152 from Abcam Category Peptide

NFE2L2 / NRF2 Antibody Blocking Peptide - LS-E27736 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NFE2L2 / NRF2 Antibody Blocking Peptide - LS-E8825 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NFE2L2 / NRF2 Antibody Blocking Peptide - LS-E13315 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Nrf2 Protein - H00004780-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Nrf2 Protein - H00004780-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Nrf2 Protein - H00004780-Q02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NFE2L2-Antibody-S40-Blocking-Peptide - BP7275d from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NRF2 protein (His tag) - 80R-4082 from Fitzgerald Category Protein Prices $275.00 Sizes 20 µg Source E.coli

Nrf2 Peptide - AC21-2546-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NFE2L2 - H00004780-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NFE2L2 - H00004780-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NFE2L2 - H00004780-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NFE2L2 - H00004780-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NFE2L2 - H00004780-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NFE2L2 - H00004780-Q02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NFE2L2 Peptide - 42-334P from ProSci Category Peptide Species Human

NRF2, NFE2L2 fusion protein - ag9469 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

NRF2, NFE2L2 fusion protein - Ag9489 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

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