NFE2L2

Gene Symbol NFE2L2
Entrez Gene 4780
Alt Symbol NRF2
Species Human
Gene Type protein-coding
Description nuclear factor, erythroid 2-like 2
Other Description HEBP1|NF-E2-related factor 2|NFE2-related factor 2|nuclear factor (erythroid-derived 2)-like 2|nuclear factor erythroid 2-related factor 2|nuclear factor erythroid-derived 2-like 2|nuclear factor, erythroid derived 2, like 2
Swissprots Q59HH2 B4E338 E9PGJ7 B2RBU2 Q96F71 Q53RW6 Q16236
Accessions AAY14710 EAX11061 EAX11062 Q16236 AB208786 BAD92023 AF323119 AAK01657 AK297838 BAG60172 AK304555 BAG65350 AK310656 AK310841 AK311395 AK311688 AK314816 BAG37339 AK316148 BAH14519 AW471118 BC011558 AAH11558 BX649047 BX649071 CV575212 DA436387 DC314553 EU446639 ABZ92168 EU831991 ACE87432 EU832084 ACE86746 EU832824 ACE87835 GQ129228 ACT64362 HM446346 ADK56055 S74017 AAB32188 NM_001145412 NP_001138884 NM_001145413 NP_001138885 NM_006164 NP_006155
Function Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region. {ECO:0000269|PubMed:11035812}.
Subcellular Location Cytoplasm, cytosol. Nucleus. Note=Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents.
Tissue Specificity Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle.
Top Pathways Protein processing in endoplasmic reticulum

Nrf2 CRISPR/Cas9 KO Plasmid (h) - sc-400017 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nrf2 HDR Plasmid (h) - sc-400017-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nrf2 Double Nickase Plasmid (h) - sc-400017-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nrf2 Double Nickase Plasmid (h2) - sc-400017-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nrf2 CRISPR Activation Plasmid (h) - sc-400017-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nrf2 CRISPR Activation Plasmid (h2) - sc-400017-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nrf2 Lentiviral Activation Particles (h) - sc-400017-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nrf2 Lentiviral Activation Particles (h2) - sc-400017-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nrf2 siRNA (h) - sc-37030 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nrf2 shRNA Plasmid (h) - sc-37030-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nrf2 shRNA (h) Lentiviral Particles - sc-37030-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nrf2 siRNA (h2) - sc-44332 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nrf2 shRNA Plasmid (h2) - sc-44332-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nrf2 shRNA (h2) Lentiviral Particles - sc-44332-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU093471 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1043 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04074 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04074

NFE2L2 siRNA (Human) - CRH3172 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Nrf2 RNAi - H00004780-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human NFE2L2 (NM_006164.4) - SHH351788 from Creative biogene

Category siRNA
Species Reactivities Human

Human NFE2L2 siRNA - orb263674 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NFE2L2 shRNA Plasmid (Human) - CHH3172 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NFE2L2 miRNA 3'UTR clone - MiUTR3H-03413 from Creative biogene

Species Reactivities Human

NFE2L2 miRNA 3'UTR clone - MiUTR3H-03414 from Creative biogene

Species Reactivities Human
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