ECSCR

Gene Symbol ECSCR
Entrez Gene 641700
Alt Symbol ARIA, ECSM2
Species Human
Gene Type protein-coding
Description endothelial cell surface expressed chemotaxis and apoptosis regulator
Other Description apoptosis regulator through modulating IAP expression|endothelial cell-specific chemotaxis regulator|endothelial cell-specific molecule 2
Swissprots B4E3H7 Q19T08 C3RSF2
Accessions Q19T08 AI699314 BC146912 AAI46913 BC146913 AAI46914 BF526332 BI834795 DQ462572 ABE73209 EU025066 ABW05062 NM_001077693 NP_001071161 NM_001293739 NP_001280668 NR_121659
Function Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2. {ECO:0000269|PubMed:18556573, ECO:0000269|PubMed:19416853}.
Subcellular Location Cell membrane; Single-pass type I membrane protein. Cytoplasm.
Tissue Specificity Highest expression in endothelial cells. Also detected in vascular smooth muscle, macrophages, lymphocytes, and mast cells. {ECO:0000269|PubMed:18556573, ECO:0000269|PubMed:19416853}.

ECSCR (S-16) - sc-241394 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ECSCR (T-13) - sc-241396 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ECSCR Antibody (aa193-205) IHC-plus™ - LS-B10278 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-ECSCR antibody IHC staining of human vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10278 concentration 5 ug/ml.

Anti-ECSCR Antibody (aa137-165, AP) - LS-C256469 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECSCR Antibody (aa137-165, FITC) - LS-C256472 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECSCR Antibody (aa137-165, APC) - LS-C256471 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECSCR Antibody (aa137-165, Biotin) - LS-C256470 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECSCR Antibody (aa137-165, PE) - LS-C256474 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECSCR Antibody (aa137-165, Azide-free, HRP) - LS-C256473 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECSCR Antibody (aa136-165) - LS-C321010 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECSCR Antibody (aa137-165) - LS-C159506 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ECSCR Antibody western blot of mouse bladder tissue lysates (35 ug/lane). The ECSCR antibody detected the ECSCR protein (arrow).

ANTI-ECSCR (C-TERM) antibody produced in rabbit - SAB1301827 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

ECSCR-Antibody-C-term - AP18022b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ECSCR Antibody (C-term) at 1:1000 dilution + A549 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 21 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

ECSM2-Antibody-C-Term - AF2410a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF2410a (1 µg/ml) staining of Human lung (A) and Human Umbical cord (B) lysates (35 µg protein in RIPA buffer). Primary incubation was 1 hour.

ECSCR Antibody - C-terminal region (OAAB13461) - OAAB13461 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

ECSCR Antibody (OAEB02611) - OAEB02611 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
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