ECSCR

Gene Symbol ECSCR
Entrez Gene 641700
Alt Symbol ARIA, ECSM2
Species Human
Gene Type protein-coding
Description endothelial cell surface expressed chemotaxis and apoptosis regulator
Other Description apoptosis regulator through modulating IAP expression|endothelial cell-specific chemotaxis regulator|endothelial cell-specific molecule 2
Swissprots B4E3H7 Q19T08 C3RSF2
Accessions Q19T08 AI699314 BC146912 AAI46913 BC146913 AAI46914 BF526332 BI834795 DQ462572 ABE73209 EU025066 ABW05062 NM_001077693 NP_001071161 NM_001293739 NP_001280668 NR_121659
Function Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2. {ECO:0000269|PubMed:18556573, ECO:0000269|PubMed:19416853}.
Subcellular Location Cell membrane; Single-pass type I membrane protein. Cytoplasm.
Tissue Specificity Highest expression in endothelial cells. Also detected in vascular smooth muscle, macrophages, lymphocytes, and mast cells. {ECO:0000269|PubMed:18556573, ECO:0000269|PubMed:19416853}.

ECSCR CRISPR/Cas9 KO Plasmid (h) - sc-409554 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ECSCR HDR Plasmid (h) - sc-409554-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ECSCR Double Nickase Plasmid (h) - sc-409554-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ECSCR Double Nickase Plasmid (h2) - sc-409554-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ECSCR CRISPR Activation Plasmid (h) - sc-409554-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ECSCR CRISPR Activation Plasmid (h2) - sc-409554-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ECSCR Lentiviral Activation Particles (h) - sc-409554-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ECSCR Lentiviral Activation Particles (h2) - sc-409554-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ECSCR siRNA (h) - sc-270116 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ECSCR shRNA Plasmid (h) - sc-270116-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ECSCR shRNA (h) Lentiviral Particles - sc-270116-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN7639 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7639 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ECSCR siRNA (Human) - CRJ8427 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ECSCR - MBS8204033 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ECSCR (NM_001077693.2) - SHH283001 from Creative biogene

Category siRNA
Species Reactivities Human

Human ECSCR siRNA - orb278928 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ECSCR shRNA Plasmid (Human) - CHJ8427 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ECSCR miRNA 3'UTR clone - MiUTR1H-03097 from Creative biogene

Species Reactivities Human
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