TLN1

Gene Symbol	TLN1
Entrez Gene	7094
Alt Symbol	ILWEQ, TLN
Species	Human
Gene Type	protein-coding
Description	talin 1
Other Description	talin-1
Swissprots	A6NMY0 Q9UPX3 Q9UHH8 Q9NZQ2 Q86YD0 Q9Y490
Accessions	AAF27330 EAW58352 EAW58353 Q9Y490 AB028950 BAA82979 AF078828 AAD13152 AF113217 AAG39288 AF177198 AAF23322 BC020881 BC042923 AAH42923 Z50170 NM_006289 NP_006280
Function	Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts (By similarity). {ECO:0000250}.
Subcellular Location	Cell projection, ruffle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cell surface {ECO:0000250}. Cell junction, focal adhesion {ECO:0000250}. Note=Colocalizes with LAYN at the membrane ruffles. Localized preferentially in focal adhesions than fibrillar adhesions (By similarity). {ECO:0000250}.
Top Pathways	Focal adhesion, HTLV-I infection, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Talin 1 peptide - ab71332 from Abcam Category Peptide

Human Talin 1 protein fragment - ab91740 from Abcam Category Protein Source E. coli Species Human

TLN1 / Talin 1 Antibody Blocking Peptide - LS-E27145 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Talin1 Partial Recombinant Protein - H00007094-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Talin1 Protein - H00007094-Q07 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Talin1 Protein - H00007094-Q06 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Talin1 Protein - H00007094-Q03 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Talin1 Protein - H00007094-Q02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Talin1 Protein - H00007094-Q08 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Talin-1 blocking peptide - GTX88357-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

Recombinant human Talin-1 (OPCA00574) - OPCA00574 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human TLN1 protein - orb246210 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human TLN1 protein - orb245233 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human Talin Protein - abx069230 from Abbexa Category Protein Source E.coli Species Human

Talin 1 Peptide - AC21-1965-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Talin-1 (TLN1) - H00007094-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Talin-1 (TLN1) - H00007094-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Talin-1 (TLN1) - H00007094-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Talin-1 (TLN1) - H00007094-Q02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Talin-1 (TLN1) - H00007094-Q03-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Talin-1 (TLN1) - H00007094-Q03-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Talin-1 (TLN1) - H00007094-Q06-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Talin-1 (TLN1) - H00007094-Q06-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Talin-1 (TLN1) - H00007094-Q07-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Talin-1 (TLN1) - H00007094-Q07-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

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