TLN1

Gene Symbol	TLN1
Entrez Gene	7094
Alt Symbol	ILWEQ, TLN
Species	Human
Gene Type	protein-coding
Description	talin 1
Other Description	talin-1
Swissprots	A6NMY0 Q9UPX3 Q9UHH8 Q9NZQ2 Q86YD0 Q9Y490
Accessions	AAF27330 EAW58352 EAW58353 Q9Y490 AB028950 BAA82979 AF078828 AAD13152 AF113217 AAG39288 AF177198 AAF23322 BC020881 BC042923 AAH42923 Z50170 NM_006289 NP_006280
Function	Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts (By similarity). {ECO:0000250}.
Subcellular Location	Cell projection, ruffle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cell surface {ECO:0000250}. Cell junction, focal adhesion {ECO:0000250}. Note=Colocalizes with LAYN at the membrane ruffles. Localized preferentially in focal adhesions than fibrillar adhesions (By similarity). {ECO:0000250}.
Top Pathways	Focal adhesion, HTLV-I infection, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Talin-1 CRISPR/Cas9 KO Plasmid (h) - sc-401342 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Talin-1 HDR Plasmid (h) - sc-401342-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Talin-1 Double Nickase Plasmid (h) - sc-401342-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Talin-1 Double Nickase Plasmid (h2) - sc-401342-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Talin CRISPR Activation Plasmid (h) - sc-401342-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Talin-1 CRISPR Activation Plasmid (h2) - sc-401342-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Talin-1 Lentiviral Activation Particles (h) - sc-401342-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Talin-1 Lentiviral Activation Particles (h2) - sc-401342-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Talin-1 siRNA (h) - sc-36610 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Talin-1 shRNA Plasmid (h) - sc-36610-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Talin-1 shRNA (h) Lentiviral Particles - sc-36610-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Talin1 RNAi - H00007094-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU087641 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1479 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit - CKOZFN1480 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit - CKOZFN1481 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1479 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1480 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1481 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

TLN1 siRNA (Human) - CRH4861 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TLN1 - MBS8210419 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human TLN1 (NM_006289.3) - SHH427896 from Creative biogene Category siRNA Species Reactivities Human

Human TLN1 siRNA - orb265363 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TLN1 shRNA Plasmid (Human) - CHH4861 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

TLN1 miRNA 3'UTR clone - MiUTR3H-02171 from Creative biogene Species Reactivities Human

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