TLN1

Gene Symbol TLN1
Entrez Gene 7094
Alt Symbol ILWEQ, TLN
Species Human
Gene Type protein-coding
Description talin 1
Other Description talin-1
Swissprots A6NMY0 Q9UPX3 Q9UHH8 Q9NZQ2 Q86YD0 Q9Y490
Accessions AAF27330 EAW58352 EAW58353 Q9Y490 AB028950 BAA82979 AF078828 AAD13152 AF113217 AAG39288 AF177198 AAF23322 BC020881 BC042923 AAH42923 Z50170 NM_006289 NP_006280
Function Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts (By similarity). {ECO:0000250}.
Subcellular Location Cell projection, ruffle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cell surface {ECO:0000250}. Cell junction, focal adhesion {ECO:0000250}. Note=Colocalizes with LAYN at the membrane ruffles. Localized preferentially in focal adhesions than fibrillar adhesions (By similarity). {ECO:0000250}.
Top Pathways Focal adhesion, HTLV-I infection, Rap1 signaling pathway

Phospho-Talin (Ser425) (D2P2M) Rabbit mAb - 13589 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D2P2M
Western blot analysis of extracts from 293T cells, untreated (-) or treated with λ phosphatase and calf intestinal phosphatase (CIP; +), using Phospho-Talin (Ser425) (D2P2M) Rabbit mAb (upper) and Talin-1 (C45F1) Rabbit mAb #4021 (lower).

Phospho-Talin (Ser425) Antibody - 5426 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from 293T cells, untreated or treated with λ and calf intestinal phosphatases using Phospho-Talin (Ser425) Antibody (upper) or Talin-1 (C45F1) Rabbit mAb #4021 (lower).

Talin-1 (C45F1) Rabbit mAb - 4021 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C45F1
Western blot analysis of extracts from various cell types using Talin-1 (C45F1) Rabbit mAb.

Talin (A-11) - sc-365460 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Talin (A-11): sc-365460. Western blot analysis of Talin expression in NIH/3T3 whole cell lysate.

Talin (C-20) - sc-7534 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Talin (C-20): sc-7534. Immunofluorescence staining of methanol-fixed NIH/3T3 cells showing cytoskeletal localization.

Talin-1 (YQ-16) - sc-81805 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Talin-1 (YQ-16): sc-81805. Western blot analysis of Talin-1 expression in Raw 264.7 whole cell lysate.

Anti-Talin 1 and 2 antibody [8D4] - ab11188 from Abcam

Prices $401.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 8D4
Central Panel: ab11188 staining Talin 1 and 2 in human PMN cells by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with paraformaldehyde, permeabilized with 0.1% TritonX-100 + 2% BSA in PBS and blocked with 2% BSA for 1 hour at 22°C. Samples were incubated with primary antibody 1/100 in blocking buffer for 4 hours at 37°C. An Alexa Fluor® 488-conjugated Goat polyclonal to mouse IgG, dilution 1/100, was used as secondary antibody. Left-hand panel: Nuclei counterstained with DAPI (blue).Right-hand panel: OverlaySee Abreview

Anti-Talin 1 antibody - ab57758 from Abcam

Prices $390.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Talin antibody (ab57758) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human small Intestine.

Anti-Talin 1 antibody - ab199869 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-Talin 1 antibody (ab199869) at 1/1000 dilutionLane 1 : Mouse brain total cell extractLane 2 : HeLa total cell extract

Anti-Talin 1 antibody [1A11] - ab110080 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1A11
ab110080, at 5µg/ml, staining Talin 1 in formalin-fixed, paraffin-embedded Human Spleen tissue by Immunohistochemistry.

Anti-Talin 1 antibody [93E12] - ab104913 from Abcam

Prices $373.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 93E12

Anti-TLN1 / Talin 1 Antibody - LS-C39475 from LifeSpan Bioscience

Prices $485.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-TLN1 / Talin 1 Antibody (N-Terminus, clone TA205) - LS-C39479 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone TA205

Anti-TLN1 / Talin 1 Antibody - LS-C144214 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TLN1 / Talin 1 Antibody (C-Terminus) - LS-C122467 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-TLN1 / Talin 1 Antibody - LS-C124631 from LifeSpan Bioscience

Prices $530.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-TLN1 / Talin 1 Antibody - LS-C132361 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-TLN1 / Talin 1 Antibody - LS-C132362 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-TLN1 / Talin 1 Antibody (clone Tal-33) - LS-C171279 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Tal-33

Anti-TLN1 / Talin 1 Antibody (clone Tal-33, Magnetic beads) - LS-C171280 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Tal-33

Anti-TLN1 / Talin 1 Antibody (clone Tal-33, Sepharose) - LS-C171281 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Tal-33

Anti-TLN1 / Talin 1 Antibody (clone 97H6) - LS-C188607 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 97H6

Anti-TLN1 / Talin 1 Antibody (aa975-1181, Biotin) - LS-C298012 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TLN1 / Talin 1 Antibody (aa975-1181, FITC) - LS-C302070 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TLN1 / Talin 1 Antibody (clone TA205) - LS-C188737 from LifeSpan Bioscience

Prices $415.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone TA205
Human peripheral blood platelets stained with Mouse anti-Human Talin
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