NAT8L

Gene Symbol	NAT8L
Entrez Gene	339983
Alt Symbol	CML3, NACED, NAT8-LIKE
Species	Human
Gene Type	protein-coding
Description	N-acetyltransferase 8-like (GCN5-related, putative)
Other Description	N-acetylaspartate synthetase|NAA synthetase|camello-like protein 3
Swissprots	Q8N9F0
Accessions	EAW82541 Q8N9F0 AK094797 BAC04426 BC010045 BC093906 AAH93906 BC093908 AAH93908 BC103748 AAI03749 NM_178557 NP_848652
Function	Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake. {ECO:0000269|PubMed:19524112}.
Subcellular Location	Cytoplasm. Membrane {ECO:0000305}; Single- pass membrane protein {ECO:0000305}. Microsome membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Mitochondrion membrane; Single-pass membrane protein. Rough endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Its enzymatic activity contribution is quantitatively larger in mitochondrial compartment than in extramitochondrial compartment.
Tissue Specificity	Expressed in brain. {ECO:0000269|PubMed:19807691}.
Top Pathways	Alanine, aspartate and glutamate metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NAT8L full length protein - ab166273 from Abcam Category Protein Source Wheat germ Species Human

NAT8L Antibody Blocking Peptide - LS-E27990 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NAT8L Protein - H00339983-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NAT8L Peptide - AC21-2752-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NAT8L - H00339983-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NAT8L - H00339983-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NAT8L fusion protein - ag12095 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant N-Acetyltransferase 8 Like Protein (NAT8L) - RPN064Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant N-Acetyltransferase 8 Like Protein (NAT8L) - RPN064Hu01 from Cloud-clone Category Protein Source E.coli Species Human

NAT8L-Blocking-Peptide-N-Term - BP21925a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NAT8L Peptide, Human - M34GP10143H from Creative Peptides Category Peptide Source Synthetic. Species Human

NAT8L Recombinant Protein (OPCD00657) - OPCD00657 from Aviva Systems Biology Category Protein Source E.coli Species Human

N-acetylaspartate synthetase (NAT8L), Recombinant Protein - MBS7022670 from MyBioSource Category Protein Prices $1,115.00, $2,100.00, $3,310.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Recombinant Human NAT8L protein, GST-tagged - NAT8L-4954H from Creative Biomart Category Protein Source Wheat Germ Species Human

Recombinant Human NAT8L protein, His-tagged - NAT8L-4994H from Creative Biomart Category Protein Source E. coli Species Human

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