NAT8L

Gene Symbol NAT8L
Entrez Gene 339983
Alt Symbol CML3, NACED, NAT8-LIKE
Species Human
Gene Type protein-coding
Description N-acetyltransferase 8-like (GCN5-related, putative)
Other Description N-acetylaspartate synthetase|NAA synthetase|camello-like protein 3
Swissprots Q8N9F0
Accessions EAW82541 Q8N9F0 AK094797 BAC04426 BC010045 BC093906 AAH93906 BC093908 AAH93908 BC103748 AAI03749 NM_178557 NP_848652
Function Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake. {ECO:0000269|PubMed:19524112}.
Subcellular Location Cytoplasm. Membrane {ECO:0000305}; Single- pass membrane protein {ECO:0000305}. Microsome membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Mitochondrion membrane; Single-pass membrane protein. Rough endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Its enzymatic activity contribution is quantitatively larger in mitochondrial compartment than in extramitochondrial compartment.
Tissue Specificity Expressed in brain. {ECO:0000269|PubMed:19807691}.
Top Pathways Alanine, aspartate and glutamate metabolism

Anti-NAT8L antibody - ab76842 from Abcam

Prices $380.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab76842 staining FLJ37478 in CHO cells transfected with mouse Nat8l cDNA by Immunocytochemistry/ Immunoflourescence. Cells were PFA-fixed and permeabilized in 0.3% Triton X-100 prior to blocking in 1% BSA for 30 minutes at 25°C. The primary antibody was diluted 1/150 in 1% BSA in PBS and incubated with the sample for 1 hour at 25°C. The secondary antibody was Cy2®-conjugated Goat- anti-Rabbit polyclonal, diluted 1/200.See Abreview

Anti-NAT8L antibody - ab69464 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-NAT8L antibody (ab69464) at 1/500 dilutionLane 1 : FLJ37478 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-NAT8L Antibody (C-Terminus) - LS-C144947 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NAT8L Antibody (C-Terminus) - LS-C146034 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NAT8L antibody LS-C146034 Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml.

Anti-NAT8L Antibody (aa211-223) - LS-C186559 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
NAT8L antibody (0.1 ug/ml) staining of fetal Mouse Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

NAT8L Antibody - NBP1-83479 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NAT8L Antibody [NBP1-83479] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY403615)

NAT8L Antibody - H00339983-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: NAT8L Antibody [H00339983-B01P] - Analysis of FLJ37478 expression in transfected 293T cell line by FLJ37478 polyclonal antibody. Lane 1: FLJ37478 transfected lysate(14.74 KDa). Lane 2: Non-transfected lysate.

Rabbit Anti-NAT8L Polyclonal Antibody - bs-11593R from Bioss

Prices $245.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-NAT8L Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11593R-A350 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-NAT8L Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11593R-A488 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-NAT8L Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11593R-A555 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-NAT8L Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11593R-A647 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-NAT8L Polyclonal Antibody, Cy3 Conjugated - bs-11593R-Cy3 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-NAT8L Polyclonal Antibody, Cy5 Conjugated - bs-11593R-Cy5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-NAT8L Polyclonal Antibody, Cy5.5 Conjugated - bs-11593R-Cy5.5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-NAT8L Polyclonal Antibody, Cy7 Conjugated - bs-11593R-Cy7 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-NAT8L Polyclonal Antibody, FITC Conjugated - bs-11593R-FITC from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-NAT8L Polyclonal Antibody, Biotin Conjugated - bs-11593R-Biotin from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-NAT8L Polyclonal Antibody, HRP Conjugated - bs-11593R-HRP from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Nat8l antibody produced in goat - SAB2502126 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-Nat8l<B>Cat. No. SAB2502126</B>: Immunoblotting (0.1 μg/mL) staining of fetal Mouse Brain lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

NAT8L antibody - C-terminal region (ARP49151_P050) - ARP49151_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Nat8l-mouse-aa211-223-Antibody-internal-region - AF3873a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF3873a (0.1 µg/ml) staining of fetal Mouse Brain lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Goat anti-Nat8l (mouse aa211-223) middle region Antibody (OAEB03053) - OAEB03053 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

NAT8L antibody - orb157929 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

NAT8L antibody - H00339983-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot analysis of FLJ37478 expression in transfected 293T cell line by FLJ37478 MaxPab polyclonal antibody. Lane 1: FLJ37478 transfected lysate(14.74 KDa). Lane 2: Non-transfected lysate.
Search more