NAT8L

Gene Symbol NAT8L
Entrez Gene 339983
Alt Symbol CML3, NACED, NAT8-LIKE
Species Human
Gene Type protein-coding
Description N-acetyltransferase 8-like (GCN5-related, putative)
Other Description N-acetylaspartate synthetase|NAA synthetase|camello-like protein 3
Swissprots Q8N9F0
Accessions EAW82541 Q8N9F0 AK094797 BAC04426 BC010045 BC093906 AAH93906 BC093908 AAH93908 BC103748 AAI03749 NM_178557 NP_848652
Function Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake. {ECO:0000269|PubMed:19524112}.
Subcellular Location Cytoplasm. Membrane {ECO:0000305}; Single- pass membrane protein {ECO:0000305}. Microsome membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Mitochondrion membrane; Single-pass membrane protein. Rough endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Its enzymatic activity contribution is quantitatively larger in mitochondrial compartment than in extramitochondrial compartment.
Tissue Specificity Expressed in brain. {ECO:0000269|PubMed:19807691}.
Top Pathways Alanine, aspartate and glutamate metabolism

NAT-8L CRISPR/Cas9 KO Plasmid (h) - sc-415533 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAT-8L HDR Plasmid (h) - sc-415533-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAT-8L Double Nickase Plasmid (h) - sc-415533-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAT-8L Double Nickase Plasmid (h2) - sc-415533-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAT-8L CRISPR Activation Plasmid (h) - sc-415533-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAT-8L CRISPR Activation Plasmid (h2) - sc-415533-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAT-8L Lentiviral Activation Particles (h) - sc-415533-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAT-8L Lentiviral Activation Particles (h2) - sc-415533-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAT-8L siRNA (h) - sc-89038 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NAT-8L shRNA Plasmid (h) - sc-89038-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NAT-8L shRNA (h) Lentiviral Particles - sc-89038-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN14972 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14972 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NAT8L siRNA (Human) - CRJ7321 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NAT8L (NM_178557.3) - SHH349540 from Creative biogene

Category siRNA
Species Reactivities Human

Human NAT8L siRNA - orb277822 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NAT8L shRNA Plasmid (Human) - CHJ7321 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NAT8L miRNA 3'UTR clone - MiUTR4H-TG05854 from Creative biogene

Species Reactivities Human
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