CYP2J2

Gene Symbol CYP2J2
Entrez Gene 1573
Alt Symbol CPJ2
Species Human
Gene Type protein-coding
Description cytochrome P450, family 2, subfamily J, polypeptide 2
Other Description CYPIIJ2|arachidonic acid epoxygenase|cytochrome P450 2J2|cytochrome P450, subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2|flavoprotein-linked monooxygenase|microsomal monooxygenase
Swissprots P51589 B2RD33 Q8TF13
Accessions AAK63192 AAM44456 AAQ93356 EAX06611 EAX06612 EAX06613 EAX06614 P51589 AB080265 BAB85489 AF144566 AAD30164 AK055088 AK315387 BAG37780 BC032594 AAH32594 DQ890862 ABM81788 DQ894017 ABM84943 U37143 AAC50370 XR_246240 XR_946558 NM_000775 NP_000766
Function This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools.
Subcellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue Specificity Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney.
Top Pathways Ovarian steroidogenesis, Inflammatory mediator regulation of TRP channels, Arachidonic acid metabolism, Linoleic acid metabolism

CYP2J2 (C-17) - sc-66361 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP2J2 (C-17): sc-66361. Western blot analysis of CYP2J2 expression in non-transfected 293T: sc-117752 (A), human CYP2J2 transfected 293T: sc-174594 (B) and Hep G2 (C) whole cell lysates.

CYP2J2 (D-6) - sc-137127 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP2J2 (D-6): sc-137127. Western blot analysis of CYP2J2 expression in non-transfected: sc-117752 (A) and human CYP2J2 transfected: sc-115223 (B) 293T whole cell lysates.

CYP2J2 (E-6) - sc-137100 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP2J2 (E-6): sc-137100. Western blot analysis of CYP2J2 expression in non-transfected: sc-117752 (A) and human CYP2J2 transfected: sc-115223 (B) 293T whole cell lysates.

CYP2J2 (D-18) - sc-66362 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CYP2J2 (K-15) - sc-66363 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CYP2J2 (H-60) - sc-67276 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CYP2J2 (H-60): sc-67276. Western blot analysis of CYP2J2 expression in mouse heart tissue extract.

CYP2J2 (T-16) - sc-66364 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP2J2 (T-16): sc-66364. Western blot analysis of human recombinant CYP2J2 fusion protein.

Anti-Cytochrome p450 2J2 antibody - ab69651 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cytochrome p450 2J2 antibody (ab69651) at 1/500 dilutionLane 1 : Extracts from A549 cellsLane 2 : Extracts from RAW264.7 cellsLane 3 : Extracts from NIH-3T3 cellsLane 4 : Extracts from NIH-3T3 cells with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-Cytochrome p450 2J2 antibody - ab151996 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cytochrome p450 2J2 antibody (ab151996) at 1/1000 dilutionLane 1 : A431 whole cell lysateLane 2 : H1299 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-Cytochrome p450 2J2 antibody - ab82361 from Abcam

Prices $304.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Cytochrome p450 2J2 antibody (ab82361) at 1/50 dilution + CEM cell line lysates at 35 µg

Anti-Cytochrome p450 2J2 antibody - ab76176 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cytochrome p450 2J2 antibody (ab76176) at 1 µg/mlLane 1 : Heart (Human) Tissue Lysate - adult normal tissue (ab29431)Lane 2 : Liver (Human) Tissue Lysate - adult normal tissue (ab29889)Lane 3 : Kidney (Human) Tissue Lysate - adult normal tissue (ab30203)Lane 4 : HEK293 (Human embryonic kidney cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-Cytochrome p450 2J2 antibody - ab54798 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-Cytochrome p450 2J2 antibody [5C9] - ab139160 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5C9
All lanes : Anti-Cytochrome p450 2J2 antibody [5C9] (ab139160) at 1/500 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY Cytochrome p450 2J2 cDNALysates/proteins at 5 µg per lane.

Anti-CYP2J2 Antibody (clone 5C5) - LS-C173348 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 5C5
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-CYP2J2 mouse monoclonal antibody.

Anti-CYP2J2 Antibody (aa335-384) - LS-C135720 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CYP2J2 antibody LS-C135720 Western blot of Fetal Heart lysate.

Anti-CYP2J2 Antibody (aa231-280) - LS-C119500 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human heart tissue, using Cytochrome P450 2J2 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-CYP2J2 Antibody (Internal) - LS-C100653 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CYP2J2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-CYP2J2 Antibody (clone 5C9) - LS-C173273 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 5C9
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-CYP2J2 mouse monoclonal antibody.

Anti-CYP2J2 Antibody (aa270-315) - LS-C313731 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP2J2 Antibody (clone 2D10) - LS-C197013 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 2D10
Detection limit for recombinant GST tagged CYP2J2 is approximately 3 ng/ml as a capture antibody.

Anti-CYP2J2 Antibody (aa103-133) - LS-C167228 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with CYP2J2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-CYP2J2 Antibody (clone 3A7) - LS-C173289 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 3A7
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP2J2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP2J2.

Anti-CYP2J2 Antibody (clone 2A9) - LS-C173275 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 2A9
Anti-CYP2J2 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CYP2J2.

Anti-CYP2J2 Antibody (clone 3A3) - LS-C173274 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 3A3
Anti-CYP2J2 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CYP2J2.

Anti-CYP2J2 Antibody (clone 4B9) - LS-C337482 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 4B9
Anti-CYP2J2 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CYP2J2.
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