Gene Symbol | CYP2J2 |
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Entrez Gene | 1573 |
Alt Symbol | CPJ2 |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome P450, family 2, subfamily J, polypeptide 2 |
Other Description | CYPIIJ2|arachidonic acid epoxygenase|cytochrome P450 2J2|cytochrome P450, subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2|flavoprotein-linked monooxygenase|microsomal monooxygenase |
Swissprots | P51589 B2RD33 Q8TF13 |
Accessions | AAK63192 AAM44456 AAQ93356 EAX06611 EAX06612 EAX06613 EAX06614 P51589 AB080265 BAB85489 AF144566 AAD30164 AK055088 AK315387 BAG37780 BC032594 AAH32594 DQ890862 ABM81788 DQ894017 ABM84943 U37143 AAC50370 XR_246240 XR_946558 NM_000775 NP_000766 |
Function | This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools. |
Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
Tissue Specificity | Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney. |
Top Pathways | Ovarian steroidogenesis, Inflammatory mediator regulation of TRP channels, Arachidonic acid metabolism, Linoleic acid metabolism |
Human Cytochrome p450 2J2 peptide - ab88195 from Abcam
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Human Cytochrome p450 2J2 protein fragment - ab158256 from Abcam
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CYP2J2 Antibody Blocking Peptide - LS-E8965 from LifeSpan Bioscience
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CYP2J2 Antibody Blocking Peptide - LS-E8966 from LifeSpan Bioscience
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CYP2J2 Antibody Blocking Peptide - LS-E22020 from LifeSpan Bioscience
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Cytochrome p450 2J2 Partial Recombinant Protein - H00001573-Q01 from Novus Biologicals
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CYP2J2-Antibody-Center-Blocking-Peptide - BP7450c from Abgent, a WuXi AppTec company
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CYP2J2-Antibody-N-term-Blocking-Peptide - BP7450a from Abgent, a WuXi AppTec company
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CYP2J2 Blocking Peptide - 33R-2525 from Fitzgerald
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Cytochrome P450 2J2 Blocking Peptide - abx062514 from Abbexa
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CYP2J2 - H00001573-Q01-10 from Acris Antibodies
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CYP2J2 - H00001573-Q01-25 from Acris Antibodies
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CYP2J2 fusion protein - ag4435 from Proteintech Group
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Cytochrome P450 2J2 Blocking Peptide - CBP1320 from Cohesion Biosciences
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CYP2J2 Peptide - BS5687P from Bioworld Technology
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Recombinant Human Cytochrome P450 2J2(CYP2J2) - CSB-YP006430HU CSB-EP006430HU CSB-BP006430HU CSB-MP006430HU from Cusabio
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CYP2J2 Protein - abx164199 from Abbexa
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CYP2J2 - TP307417 from Acris Antibodies
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CYP2J2 Peptide, Human - M34GP03963H from Creative Peptides
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Cytochrome P450 2J2 (CYP2J2), Recombinant Protein - MBS718215 from MyBioSource
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CYP2J2 peptide - orb217183 from Biorbyt
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