Gene Symbol |
TDO2
|
Entrez Gene |
6999
|
Alt Symbol |
TDO, TO, TPH2, TRPO
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
tryptophan 2,3-dioxygenase
|
Other Description |
TDO|TO|TRPO|tryptamin 2,3-dioxygenase|tryptophan oxygenase|tryptophan pyrrolase|tryptophanase
|
Swissprots |
A8K053 P48775
|
Accessions |
EAX04884 EAX04885 EAX04886 P48775 AA705255 AK289418 BAF82107 AK307741 BC005355 AAH05355 BG616664 BX647341 EU831460 ACE87147 EU831547 ACE86466 HQ447298 ADQ31785 U32989 AAB08514 NM_005651 NP_005642
|
Function |
Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin (By similarity). {ECO:0000250}.
|
Top Pathways |
Tryptophan metabolism
|