Gene Symbol | TDO2 |
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Entrez Gene | 6999 |
Alt Symbol | TDO, TO, TPH2, TRPO |
Species | Human |
Gene Type | protein-coding |
Description | tryptophan 2,3-dioxygenase |
Other Description | TDO|TO|TRPO|tryptamin 2,3-dioxygenase|tryptophan oxygenase|tryptophan pyrrolase|tryptophanase |
Swissprots | A8K053 P48775 |
Accessions | EAX04884 EAX04885 EAX04886 P48775 AA705255 AK289418 BAF82107 AK307741 BC005355 AAH05355 BG616664 BX647341 EU831460 ACE87147 EU831547 ACE86466 HQ447298 ADQ31785 U32989 AAB08514 NM_005651 NP_005642 |
Function | Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin (By similarity). {ECO:0000250}. |
Top Pathways | Tryptophan metabolism |
TDO2 CRISPR/Cas9 KO Plasmid (h) - sc-402482 from Santa Cruz Biotechnology
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TDO2 HDR Plasmid (h) - sc-402482-HDR from Santa Cruz Biotechnology
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TDO2 Double Nickase Plasmid (h) - sc-402482-NIC from Santa Cruz Biotechnology
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TDO2 Double Nickase Plasmid (h2) - sc-402482-NIC-2 from Santa Cruz Biotechnology
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TDO2 CRISPR Activation Plasmid (h) - sc-402482-ACT from Santa Cruz Biotechnology
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TDO2 CRISPR Activation Plasmid (h2) - sc-402482-ACT-2 from Santa Cruz Biotechnology
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TDO2 Lentiviral Activation Particles (h) - sc-402482-LAC from Santa Cruz Biotechnology
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TDO2 Lentiviral Activation Particles (h2) - sc-402482-LAC-2 from Santa Cruz Biotechnology
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TDO2 siRNA (h) - sc-89222 from Santa Cruz Biotechnology
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TDO2 shRNA Plasmid (h) - sc-89222-SH from Santa Cruz Biotechnology
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TDO2 shRNA (h) Lentiviral Particles - sc-89222-V from Santa Cruz Biotechnology
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TDO2 RNAi - H00006999-R01 from Novus Biologicals
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MISSION® esiRNA - EHU012871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21182 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21182 from Sigma-Aldrich
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TDO2 siRNA (Human) - CRH4778 from Cohesion Biosciences
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TDO2 - MBS8234045 from MyBioSource
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TDO2 CRISPR/Cas9 KO Plasmid (h2) - sc-402482-KO-2 from Santa Cruz Biotechnology
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TDO2 HDR Plasmid (h2) - sc-402482-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human TDO2 (NM_005651.3) - SHH425276 from Creative biogene
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Human TDO2 siRNA - orb265280 from Biorbyt
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TDO2 shRNA Plasmid (Human) - CHH4778 from Cohesion Biosciences
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TDO2 miRNA 3'UTR clone - MiUTR3H-02311 from Creative biogene
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