Gene Symbol | TDO2 |
---|---|
Entrez Gene | 6999 |
Alt Symbol | TDO, TO, TPH2, TRPO |
Species | Human |
Gene Type | protein-coding |
Description | tryptophan 2,3-dioxygenase |
Other Description | TDO|TO|TRPO|tryptamin 2,3-dioxygenase|tryptophan oxygenase|tryptophan pyrrolase|tryptophanase |
Swissprots | A8K053 P48775 |
Accessions | EAX04884 EAX04885 EAX04886 P48775 AA705255 AK289418 BAF82107 AK307741 BC005355 AAH05355 BG616664 BX647341 EU831460 ACE87147 EU831547 ACE86466 HQ447298 ADQ31785 U32989 AAB08514 NM_005651 NP_005642 |
Function | Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin (By similarity). {ECO:0000250}. |
Top Pathways | Tryptophan metabolism |