GFRA2

Gene Symbol GFRA2
Entrez Gene 2675
Alt Symbol GDNFRB, NRTNR-ALPHA, NTNRA, RETL2, TRNR2
Species Human
Gene Type protein-coding
Description GDNF family receptor alpha 2
Other Description GDNF family receptor alpha-2|GDNF receptor beta|GDNFR-alpha-2|GDNFR-beta|GFR-alpha 2|NTNR-alpha|PI-linked cell-surface accessory protein|RET ligand 2|TGF-beta-related neurotrophic factor receptor 2|TRN receptor, GPI-anchored|glial cell line derived neurotrophic factor receptor, beta|neurturin receptor alpha
Swissprots O15328 Q6GTR9 Q7Z5C2 O15316 E9PD47 Q58J92 O00451
Accessions CAM55948 EAW63742 O00451 AF002700 AAC52036 AK299623 BAG61551 AY326396 AAP88378 AY941828 AAX46325 BC041688 AAH41688 JF432396 ADZ15613 U93703 AAB61922 U97145 AAC51647 XM_005273475 XP_005273532 XM_006716327 XP_006716390 XM_011544484 XP_011542786 XM_011544485 XP_011542787 NM_001165038 NP_001158510 NM_001165039 NP_001158511 NM_001495 NP_001486
Function Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.
Subcellular Location Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.
Tissue Specificity Isoform 1 is found in both brain and placenta.

GFRα-2 (H-89) - sc-28953 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GFRα-2 (H-89): sc-28953. Western blot analysis of GFRα-2 expression in non-transfected 293T: sc-117752 (A) and human GFRα-2 transfected 293T: sc-115868 (B) whole cell lysates and rat testis (C) tissue extract.

GFRα-2 (N-20) - sc-7136 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

GFRα-2 (C-20) - sc-7414 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GFRα-2 (C-20): sc-7414. Immunofluorescence staining of methanol-fixed SK-N-SH cells showing membrane localization.

Anti-GDNF Receptor alpha 2 antibody - ab8027 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GDNF Receptor alpha 2 antibody (ab8027) at 1/1000 dilution + HeLa total cell lysateObserved band size : 52 kDa (why is the actual band size different from the predicted?)

Anti-GDNF Receptor alpha 2 antibody - ab62124 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GDNF Receptor alpha 2 antibody (ab62124) at 1/1000 dilution + HeLa total cell lysate

Anti-GDNF Receptor alpha 2 antibody - ab19146 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GDNF Receptor alpha 2 antibody [MM0309-11G34] - ab89342 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0309-11G34

Anti-GFR alpha 2 antibody - ab123260 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-GFR alpha 2 antibody (ab123260) at 1/100 dilution + NCI-H292 cell line lysates at 35 µg

Anti-GFRA2 Antibody (aa376-390) - LS-C66500 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GFRA2 Antibody - LS-C149958 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-GFRA2 Antibody - LS-C150113 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-GFRA2 Antibody - LS-C26631 from LifeSpan Bioscience

Prices $360.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of GFRa-2 antibody on HeLa total cell lysate.

Anti-GFRA2 Antibody - LS-C194990 from LifeSpan Bioscience

Prices $650.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GFRA2 Antibody (aa361-390, APC) - LS-C259505 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GFRA2 Antibody (aa361-390, Biotin) - LS-C259506 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GFRA2 Antibody (aa361-390, AP) - LS-C259504 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GFRA2 Antibody (aa361-390, Azide-free, HRP) - LS-C259508 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GFRA2 Antibody (aa361-390, FITC) - LS-C259507 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GFRA2 Antibody (aa361-390, PE) - LS-C259509 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GFRA2 Antibody (aa377-391) - LS-C265 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry of GFR alpha 2 in HeLa cells with GFR alpha 2 antibody at 5 ug/ml.

Anti-GFRA2 Antibody (aa360-390) - LS-C321610 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GFRA2 Antibody - LS-C26873 from LifeSpan Bioscience

Prices $360.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of GFRa-2 in HeLa total cell lysate with GFRa-2 antibody at 1:1000 dilution.

Anti-GFRA2 Antibody (aa362-411) - LS-C81873 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal brain lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-GFRA2 Antibody (aa361-390) - LS-C166450 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
GFRA2 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The GFRA2 antibody detected the GFRA2 protein (arrow).

GFR alpha-2/GDNF R alpha-2 Antibody [Unconjugated] - AF429 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
GFR alpha ‑2/GDNF R alpha ‑2 was detected in perfusion fixed frozen sections of mouse dorsal root ganglion using Goat Anti-Human/Mouse GFR alpha ‑2/GDNF R alpha ‑2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF429) at 1.7 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to plasma membrane of sensory neurons. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.
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