| Gene Symbol |
GFRA2
|
| Entrez Gene |
2675
|
| Alt Symbol |
GDNFRB, NRTNR-ALPHA, NTNRA, RETL2, TRNR2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
GDNF family receptor alpha 2
|
| Other Description |
GDNF family receptor alpha-2|GDNF receptor beta|GDNFR-alpha-2|GDNFR-beta|GFR-alpha 2|NTNR-alpha|PI-linked cell-surface accessory protein|RET ligand 2|TGF-beta-related neurotrophic factor receptor 2|TRN receptor, GPI-anchored|glial cell line derived neurotrophic factor receptor, beta|neurturin receptor alpha
|
| Swissprots |
O15328 Q6GTR9 Q7Z5C2 O15316 E9PD47 Q58J92 O00451
|
| Accessions |
CAM55948 EAW63742 O00451 AF002700 AAC52036 AK299623 BAG61551 AY326396 AAP88378 AY941828 AAX46325 BC041688 AAH41688 JF432396 ADZ15613 U93703 AAB61922 U97145 AAC51647 XM_005273475 XP_005273532 XM_006716327 XP_006716390 XM_011544484 XP_011542786 XM_011544485 XP_011542787 NM_001165038 NP_001158510 NM_001165039 NP_001158511 NM_001495 NP_001486
|
| Function |
Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.
|
| Tissue Specificity |
Isoform 1 is found in both brain and placenta.
|
![Western Blot: GDNF Receptor alpha 2 Overexpression Lysate (Adult Normal) [NBL1-11052] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GDNF Receptor alpha 2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6688_GDNF%2520Receptor%2520alpha%25202%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11052-img0002.jpg)