Gene Symbol | GFRA2 |
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Entrez Gene | 2675 |
Alt Symbol | GDNFRB, NRTNR-ALPHA, NTNRA, RETL2, TRNR2 |
Species | Human |
Gene Type | protein-coding |
Description | GDNF family receptor alpha 2 |
Other Description | GDNF family receptor alpha-2|GDNF receptor beta|GDNFR-alpha-2|GDNFR-beta|GFR-alpha 2|NTNR-alpha|PI-linked cell-surface accessory protein|RET ligand 2|TGF-beta-related neurotrophic factor receptor 2|TRN receptor, GPI-anchored|glial cell line derived neurotrophic factor receptor, beta|neurturin receptor alpha |
Swissprots | O15328 Q6GTR9 Q7Z5C2 O15316 E9PD47 Q58J92 O00451 |
Accessions | CAM55948 EAW63742 O00451 AF002700 AAC52036 AK299623 BAG61551 AY326396 AAP88378 AY941828 AAX46325 BC041688 AAH41688 JF432396 ADZ15613 U93703 AAB61922 U97145 AAC51647 XM_005273475 XP_005273532 XM_006716327 XP_006716390 XM_011544484 XP_011542786 XM_011544485 XP_011542787 NM_001165038 NP_001158510 NM_001165039 NP_001158511 NM_001495 NP_001486 |
Function | Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. |
Subcellular Location | Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}. |
Tissue Specificity | Isoform 1 is found in both brain and placenta. |
Active human GDNF Receptor alpha 2 protein fragment - ab167734 from Abcam
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Active human GDNF Receptor alpha 2 protein fragment - ab174085 from Abcam
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Human GDNF Receptor alpha 2 peptide - ab39769 from Abcam
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Human GDNF Receptor alpha 2 protein fragment - ab151840 from Abcam
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GFRA2 Antibody Blocking Peptide - LS-E3224 from LifeSpan Bioscience
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GFRA2 Antibody Blocking Peptide - LS-E29849 from LifeSpan Bioscience
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GFR alpha-2/GDNF R alpha-2 Blocking Peptide - NBP1-77042PEP from Novus Biologicals
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GFRA2-Antibody-C-term-Blocking-Peptide - BP14374b from Abgent, a WuXi AppTec company
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Recombinant Human GFR alpha-2 Fc Chimera, CF - 613-FR-100 from R&D Systems
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Human GFRA2 His tag protein - orb83655 from Biorbyt
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Human GFRalpha 2 protein - orb49403 from Biorbyt
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Mouse GFRA2 His tag protein - orb83675 from Biorbyt
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GFRA2 Blocking Peptide - 33R-6924 from Fitzgerald
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GFRA2 / GDNFR-beta Control Peptide - AP30362CP-N from Acris Antibodies
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GDNF Family Receptor alpha -2, GFRA2, Human, Recombinant - 19-C472 from ARP American Research Products
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GFR alpha 2 Peptide - 1135P from ProSci
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GFRA 2 Recombinant Protein - 96-346 from ProSci
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GFRA 2 Recombinant Protein - 96-347 from ProSci
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GFRA2 fusion protein - Ag16893 from Proteintech Group
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GFRA2 fusion protein - ag17462 from Proteintech Group
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Recombinant Human GFRA2 Protein - BP001419-C472 from Syd Labs
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Recombinant Human GFRA2, His tagged - GFRA2-3162H from Creative Biomart
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Recombinant Human GDNF Family Receptor Alpha 2 - GFRA2-1619H from Creative Biomart
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Recombinant Human GFRA2, Fc Chimera - GFRA2-893H from Creative Biomart
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GFRA2 / GDNFRB - PN201653 from Elabscience
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