FPR1

Gene Symbol FPR1
Entrez Gene 2357
Alt Symbol FMLP, FPR
Species Human
Gene Type protein-coding
Description formyl peptide receptor 1
Other Description N-formylpeptide chemoattractant receptor|fMLP receptor|fMet-Leu-Phe receptor
Swissprots Q9NS48 Q86U52 P21462 Q7Z6A4 Q14939
Accessions AAA16863 AAF87842 AAP58403 EAW72040 EAW72041 EAW72042 P21462 AK314935 BAG37441 BC005315 AAH05315 BQ016000 BT007429 AAP36097 CB993626 M37128 AAA36362 M60626 AAA35846 M60627 AAA35847 S49810 AAD14906 NM_001193306 NP_001180235 NM_002029 NP_002020
Function High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors (PubMed:2161213, PubMed:2176894, PubMed:10514456, PubMed:15153520). Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release (PubMed:2161213, PubMed:1712023, PubMed:15153520). This response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system (PubMed:1712023, PubMed:10514456). {ECO:0000269|PubMed:10514456, ECO:0000269|PubMed:15153520, ECO:0000269|PubMed:2161213, ECO:0000269|PubMed:2176894, ECO:0000303|PubMed:10514456, ECO:0000303|PubMed:1712023, ECO:0000303|PubMed:2161213, ECO:0000303|PubMed:2176894}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:15153520, ECO:0000269|PubMed:2176894, ECO:0000305|PubMed:10514456}; Multi- pass membrane protein {ECO:0000255}.
Tissue Specificity Neutrophils.
Top Pathways Staphylococcus aureus infection, Rap1 signaling pathway, Neuroactive ligand-receptor interaction

FPR (H-230) - sc-30016 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-FPR1 antibody - ab113531 from Abcam

Prices $384.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-FPR1 antibody (ab113531) at 1/500 dilutionLane 1 : K562 cell extractLane 2 : K562 cell extract with immunizing peptide

Anti-FPR1 antibody - ab101659 from Abcam

Host Rabbit
Clonality Polyclonal
IHC image of FPR1 staining in human spleen formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab101659, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-FPR1 antibody - ab128296 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC image of FPR1 staining in human spleen formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab128296, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-FPR1 antibody - Extracellular domain - ab150533 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed, paraffin embedded Human tonsil tissue labeling FPR1 with ab150533 at 2 µg/ml .

Anti-FPR1 / FPR Antibody (aa176-190) IHC-plus™ - LS-B2027 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FPR1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2027 concentration 10 ug/ml.

Anti-FPR1 / FPR Antibody (aa165-193, AP) - LS-C214364 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FPR1 / FPR Antibody (Extracellular Domain) IHC-plus™ - LS-A2085 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FPR1 antibody LS-A2085 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-FPR1 / FPR Antibody (aa151-200) - LS-C120655 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of A549 cells, using FPR1 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-FPR1 / FPR Antibody (aa165-193, APC) - LS-C214365 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FPR1 / FPR Antibody (aa165-193, FITC) - LS-C214366 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FPR1 / FPR Antibody (aa165-193, Biotin) - LS-C214367 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FPR1 / FPR Antibody (aa165-193) - LS-C159680 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
FPR1 Antibody western blot of A549 cell line lysates (35 ug/lane). The FPR1 antibody detected the FPR1 protein (arrow).

Anti-FPR1 / FPR Antibody (aa174-223) - LS-C151138 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
FPR1 / FPR antibody Western Blot of Fetal Heart.

Anti-FPR1 / FPR Antibody (aa165-193, Azide-free, HRP) - LS-C214368 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FPR1 / FPR Antibody (aa165-193, PE) - LS-C214369 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FPR1 / FPR Antibody (aa148-197) - LS-C291960 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FPR1 / FPR Antibody (aa207-252) - LS-C313759 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FPR1 / FPR Antibody (aa203-248) - LS-C313761 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FPR1 / FPR Antibody (aa164-193) - LS-C321456 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FPR1 / FPR Antibody (Extracellular Domain) IHC-plus™ - LS-A2086 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FPR1 antibody LS-A2086 IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-FPR1 / FPR Antibody (aa155-204) IHC-plus™ - LS-B4873 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FPR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4873 concentration 5 ug/ml.

Anti-FPR1 / FPR Antibody (Extracellular Domain) IHC-plus™ - LS-A2087 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FPR1 antibody LS-A2087 IHC of human spleen, red pulp. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-FPR1 / FPR Antibody (C-Terminus) IHC-plus™ - LS-A2088 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FPR1 antibody LS-A2088 IHC of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

FPR1 Antibody - NB100-56473 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: FPR1 Antibody [NB100-56473] - Western blot analysis of FPR1 in the 1) absence and 2) presence of immunizing peptide in human liver lysate using NB100-56473 at 1 ug/ml.
Search more