FPR1

Gene Symbol FPR1
Entrez Gene 2357
Alt Symbol FMLP, FPR
Species Human
Gene Type protein-coding
Description formyl peptide receptor 1
Other Description N-formylpeptide chemoattractant receptor|fMLP receptor|fMet-Leu-Phe receptor
Swissprots Q9NS48 Q86U52 P21462 Q7Z6A4 Q14939
Accessions AAA16863 AAF87842 AAP58403 EAW72040 EAW72041 EAW72042 P21462 AK314935 BAG37441 BC005315 AAH05315 BQ016000 BT007429 AAP36097 CB993626 M37128 AAA36362 M60626 AAA35846 M60627 AAA35847 S49810 AAD14906 NM_001193306 NP_001180235 NM_002029 NP_002020
Function High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors (PubMed:2161213, PubMed:2176894, PubMed:10514456, PubMed:15153520). Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release (PubMed:2161213, PubMed:1712023, PubMed:15153520). This response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system (PubMed:1712023, PubMed:10514456). {ECO:0000269|PubMed:10514456, ECO:0000269|PubMed:15153520, ECO:0000269|PubMed:2161213, ECO:0000269|PubMed:2176894, ECO:0000303|PubMed:10514456, ECO:0000303|PubMed:1712023, ECO:0000303|PubMed:2161213, ECO:0000303|PubMed:2176894}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:15153520, ECO:0000269|PubMed:2176894, ECO:0000305|PubMed:10514456}; Multi- pass membrane protein {ECO:0000255}.
Tissue Specificity Neutrophils.
Top Pathways Staphylococcus aureus infection, Rap1 signaling pathway, Neuroactive ligand-receptor interaction

FPR CRISPR/Cas9 KO Plasmid (h) - sc-418173 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FPR HDR Plasmid (h) - sc-418173-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FPR Double Nickase Plasmid (h) - sc-418173-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FPR Double Nickase Plasmid (h2) - sc-418173-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FPR CRISPR Activation Plasmid (h) - sc-418173-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FPR CRISPR Activation Plasmid (h2) - sc-418173-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FPR Lentiviral Activation Particles (h) - sc-418173-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FPR Lentiviral Activation Particles (h2) - sc-418173-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FPR siRNA (h) - sc-40121 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FPR shRNA Plasmid (h) - sc-40121-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FPR shRNA (h) Lentiviral Particles - sc-40121-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FPR1 RNAi - H00002357-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU036761 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN8926 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8926 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00352 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00352

FPR1 siRNA (Human) - CRH1648 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FPR1 - MBS8233909 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FPR CRISPR/Cas9 KO Plasmid (h2) - sc-418173-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FPR HDR Plasmid (h2) - sc-418173-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Human FPR1 siRNA - orb262150 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FPR1 shRNA Plasmid (Human) - CHH1648 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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