Gene Symbol | ATF7 |
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Entrez Gene | 11016 |
Alt Symbol | ATFA |
Species | Human |
Gene Type | protein-coding |
Description | activating transcription factor 7 |
Other Description | cyclic AMP-dependent transcription factor ATF-7|transcription factor ATF-A |
Swissprots | Q8IVR8 P17544 B4DQL4 A5D6Y4 Q9UD83 B2RMP1 Q13814 |
Accessions | EAW96723 EAW96724 P17544 AA679547 AK298853 BAG60976 AK302907 BAG64077 AK310355 AK313507 BAG36287 BC032433 BC042363 AAH42363 BC136302 AAI36303 BC140006 AAI40007 BP279417 BP312300 BQ184780 DB047160 DB490927 X52943 CAA37118 X57197 CAA40483 XM_005268587 XP_005268644 XM_011537776 XP_011536078 XM_011537777 XP_011536079 XM_011537778 XP_011536080 NM_001130059 NM_001130060 NP_001123532 NM_001206682 NP_001193611 NM_001206683 NP_001193612 NM_006856 NP_006847 NR_073163 |
Function | Isoform 5/ATF-4 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978, ECO:0000269|PubMed:17264123}. Nucleus, nucleoplasm {ECO:0000269|PubMed:17264123}. Note=Mainly nucleoplasmic. Restricted distribution to the perinuculear region. The sumoylated form locates to the nuclear periphery. |
Tissue Specificity | Expressed in heart, lung and skeletal muscle. Isoform 4 is expressed in various tissues including heart, brain, placenta, lung and skeletal muscle. Highest levels in skeletal muscle. Lowest in lung and placenta. {ECO:0000269|PubMed:8288576}. |
ATF-7 (H-53) - sc-366261 from Santa Cruz Biotechnology
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ATF-7 (S-15) - sc-19764 from Santa Cruz Biotechnology
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Anti-ATF7 antibody - ab77083 from Abcam
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Anti-ATF7 antibody - ab87844 from Abcam
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Anti-ATF7 antibody - ab65064 from Abcam
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Anti-ATF7 antibody - ab89523 from Abcam
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Anti-ATF7 antibody - ab123046 from Abcam
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Anti-ATF7 antibody - ab192921 from Abcam
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Anti-ATF7 antibody [EPR13556] - ab183507 from Abcam
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Anti-ATF7 Antibody (clone 49C3a) - LS-C184819 from LifeSpan Bioscience
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Anti-ATF7 Antibody (aa444-494) - LS-C289169 from LifeSpan Bioscience
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Anti-ATF7 Antibody - LS-C306424 from LifeSpan Bioscience
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Anti-ATF7 Antibody (C-Terminus) - LS-C31157 from LifeSpan Bioscience
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Anti-ATF7 Antibody (clone 49C3a) - LS-C342821 from LifeSpan Bioscience
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Anti-ATF7 Antibody (Internal) - LS-C345769 from LifeSpan Bioscience
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Anti-ATF7 Antibody (aa41-90) - LS-C118801 from LifeSpan Bioscience
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Anti-ATF7 Antibody (aa71-120) - LS-C112356 from LifeSpan Bioscience
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Anti-ATF7 Antibody (aa50-270) - LS-C292618 from LifeSpan Bioscience
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Anti-ATF7 Antibody (aa397-446) - LS-C146076 from LifeSpan Bioscience
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Anti-ATF7 Antibody (Phe74) - LS-C176739 from LifeSpan Bioscience
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Anti-ATF7 Antibody (C-Terminus) IHC-plus™ - LS-B2737 from LifeSpan Bioscience
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ATF7 Antibody - NB300-899 from Novus Biologicals
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ATF7 Antibody - NBP1-88876 from Novus Biologicals
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ATF7 Antibody - NBP1-30899 from Novus Biologicals
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ATF7 Antibody - H00011016-B01P from Novus Biologicals
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