Gene Symbol | ATF7 |
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Entrez Gene | 11016 |
Alt Symbol | ATFA |
Species | Human |
Gene Type | protein-coding |
Description | activating transcription factor 7 |
Other Description | cyclic AMP-dependent transcription factor ATF-7|transcription factor ATF-A |
Swissprots | Q8IVR8 P17544 B4DQL4 A5D6Y4 Q9UD83 B2RMP1 Q13814 |
Accessions | EAW96723 EAW96724 P17544 AA679547 AK298853 BAG60976 AK302907 BAG64077 AK310355 AK313507 BAG36287 BC032433 BC042363 AAH42363 BC136302 AAI36303 BC140006 AAI40007 BP279417 BP312300 BQ184780 DB047160 DB490927 X52943 CAA37118 X57197 CAA40483 XM_005268587 XP_005268644 XM_011537776 XP_011536078 XM_011537777 XP_011536079 XM_011537778 XP_011536080 NM_001130059 NM_001130060 NP_001123532 NM_001206682 NP_001193611 NM_001206683 NP_001193612 NM_006856 NP_006847 NR_073163 |
Function | Isoform 5/ATF-4 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978, ECO:0000269|PubMed:17264123}. Nucleus, nucleoplasm {ECO:0000269|PubMed:17264123}. Note=Mainly nucleoplasmic. Restricted distribution to the perinuculear region. The sumoylated form locates to the nuclear periphery. |
Tissue Specificity | Expressed in heart, lung and skeletal muscle. Isoform 4 is expressed in various tissues including heart, brain, placenta, lung and skeletal muscle. Highest levels in skeletal muscle. Lowest in lung and placenta. {ECO:0000269|PubMed:8288576}. |
Human ATF7 full length protein - ab161243 from Abcam
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Human ATF7 protein fragment - ab161244 from Abcam
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ATF7 Antibody Blocking Peptide - LS-E10857 from LifeSpan Bioscience
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ATF7 Antibody Blocking Peptide - LS-E10858 from LifeSpan Bioscience
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ATF7 Antibody Blocking Peptide - LS-E25269 from LifeSpan Bioscience
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ATF7 Antibody Blocking Peptide - LS-E13999 from LifeSpan Bioscience
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Recombinant Human ATF7 Protein - H00011016-P01 from Novus Biologicals
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Recombinant Human ATF7 Protein - H00011016-Q01 from Novus Biologicals
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ATF7 blocking peptide - GTX89982-PEP from GeneTex
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ATF7 Peptide - AC21-0097-P from Abcore
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ATF7 - H00011016-P01-10 from Acris Antibodies
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ATF7 - H00011016-P01-25 from Acris Antibodies
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ATF7 - H00011016-Q01-10 from Acris Antibodies
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ATF7 - H00011016-Q01-25 from Acris Antibodies
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ATF7 Peptide - 45-305P from ProSci
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Recombinant Activating Transcription Factor 7 (ATF7) - RPB398Hu01 from Uscn Life Science Inc.
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Recombinant Activating Transcription Factor 7 (ATF7) - RPB398Mu01 from Uscn Life Science Inc.
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ATF7 Blocking Peptide - CBP3389 from Cohesion Biosciences
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ATF-7 (F74) Peptide - BS1941P from Bioworld Technology
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Recombinant Activating Transcription Factor 7 (ATF7) - RPB398Hu01 from Cloud-clone
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Recombinant Human Cyclic AMP-dependent transcription factor ATF-7(ATF7) - CSB-YP002279HU CSB-EP002279HU CSB-BP002279HU CSB-MP002279HU from Cusabio
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Activating transcription factor 7-interacting protein 1(atf7ip) ,partial - MBS2031382 from MyBioSource
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Activating transcription factor 7-interacting protein 2 (ATF7IP2) - MBS2030768 from MyBioSource
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Activating Transcription Factor 7 Protein (Recombinant) - abx166814 from Abbexa
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ATF7 Protein - abx164069 from Abbexa
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