SLC7A7

Gene Symbol	SLC7A7
Entrez Gene	9056
Alt Symbol	LAT3, LPI, MOP-2, Y+LAT1, y+LAT-1
Species	Human
Gene Type	protein-coding
Description	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
Other Description	Y+L amino acid transporter 1|monocyte amino acid permease 2|solute carrier family 7 (cationic amino acid transporter, y+ system), member 7|y(+)L-type amino acid transporter 1
Swissprots	Q86U07 Q9P2V5 B2RAU0 Q53XC1 O95984 D3DS26 Q9UM01
Accessions	BAA95120 EAW66245 EAW66246 EAW66247 EAW66248 Q9UM01 AB011263 BAB11849 AB020532 BAA87623 AB209591 BAD92828 AF092032 AAC83706 AJ130718 CAA10198 AK025377 AK301219 BAG62792 AK309128 AK314351 BAG36987 AL365450 AL365451 AL365452 BC003062 AAH03062 BC010107 AAH10107 BX161519 CAD61952 BX248291 CAD62619 DA044956 DA638578 DA950997 DA991442 DB170842 DQ891835 ABM82761 DQ895021 ABM85947 Y18474 CAB40136 XM_006720302 XP_006720365 XM_011537298 XP_011535600 XM_011537299 XP_011535601 NM_001126105 NP_001119577 NM_001126106 NP_001119578 NR_040448 NM_003982
Function	Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L- arginine in monocytes. {ECO:0000269|PubMed:14603368, ECO:0000269|PubMed:15280038, ECO:0000269|PubMed:17329401, ECO:0000269|PubMed:9829974, ECO:0000269|PubMed:9878049}.
Subcellular Location	Basolateral cell membrane {ECO:0000269|PubMed:15756301}; Multi-pass membrane protein {ECO:0000269|PubMed:15756301}.
Tissue Specificity	Highest expression in kidney and peripheral blood leukocytes. Weaker expression is observed in lung, heart, placenta, spleen, testis and small intestine. Expressed in normal fibroblasts and those from LPI patients. Also expressed in HUVECs, monocytes, retinal pigment epithelial cells, and various carcinoma cell lines, with highest expression in a colon-carcinoma cell line. {ECO:0000269|PubMed:10080183, ECO:0000269|PubMed:11078698, ECO:0000269|PubMed:11742806, ECO:0000269|PubMed:15280038, ECO:0000269|PubMed:17197568, ECO:0000269|PubMed:17329401, ECO:0000269|PubMed:9829974}.
Top Pathways	Protein digestion and absorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SLC7A7 ELISA Kit (Sandwich ELISA) - LS-F9473 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.114 ng/ml Range 0.313-20 ng/ml

L-Type Amino Acid Transporter 1 (y+LAT1), Human, ELISA Kit - SEE417Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.114ng/mL Range 0.312-20ng/mL

Y+L amino acid transporter 1 (SLC7A7), Human, ELISA Kit - E01Y0001 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Y+L amino acid transporter 1, ELISA Kit - MBS280633 from MyBioSource Category ELISA Kit Prices $425.00, $720.00, $3,160.00, $6,055.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Y+L amino acid transporter 1 (SLC7A7), ELISA Kit - MBS7250695 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Y+L amino acid transporter 1 (SLC7A7), ELISA Kit - MBS7206678 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Y+L amino acid transporter 1 (SLC7A7), ELISA Kit - MBS7202076 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Y+L amino acid transporter 1 (SLC7A7), ELISA Kit - MBS7248682 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Y+L amino acid transporter 1 (SLC7A7), ELISA Kit - MBS7242550 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Y+L amino acid transporter 1 (SLC7A7), ELISA Kit - MBS7253095 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Y+L amino acid transporter 1 (SLC7A7), ELISA Kit - MBS7230086 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Y+L amino acid transporter 1 (SLC7A7), ELISA Kit - MBS7239560 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Y+L amino acid transporter 1 (SLC7A7), ELISA Kit - MBS7228917 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Y+L amino acid transporter 1 (SLC7A7), ELISA Kit - MBS7219710 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Y+L amino acid transporter 1 (SLC7A7), ELISA Kit - MBS7237375 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for L-Type Amino Acid Transporter 1 (y+LAT1) - SEE417Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.114ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for L-Type Amino Acid Transporter 1 (y+LAT1) - SEE417Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.114ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human y+LAT1 ELISA Kit - abx153527 from Abbexa Category ELISA Kit Sensitivity 0.114 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human y+LAT1 ELISA Kit - abx573138 from Abbexa Category ELISA Kit

Human y+LAT1 ELISA Kit - E022036 from Biobool Category ELISA Kit Sensitivity Typically less than 0.114ng/mL.

Human SLC7A7 ELISA Kit - E103152 from Biobool Category ELISA Kit

L-Type Amino Acid Transporter 1 (y+LAT1), ELISA Kit - MBS456174 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.114ng/mL Range 0.312-20ng/mL

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