SLC7A7

Gene Symbol	SLC7A7
Entrez Gene	9056
Alt Symbol	LAT3, LPI, MOP-2, Y+LAT1, y+LAT-1
Species	Human
Gene Type	protein-coding
Description	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
Other Description	Y+L amino acid transporter 1|monocyte amino acid permease 2|solute carrier family 7 (cationic amino acid transporter, y+ system), member 7|y(+)L-type amino acid transporter 1
Swissprots	Q86U07 Q9P2V5 B2RAU0 Q53XC1 O95984 D3DS26 Q9UM01
Accessions	BAA95120 EAW66245 EAW66246 EAW66247 EAW66248 Q9UM01 AB011263 BAB11849 AB020532 BAA87623 AB209591 BAD92828 AF092032 AAC83706 AJ130718 CAA10198 AK025377 AK301219 BAG62792 AK309128 AK314351 BAG36987 AL365450 AL365451 AL365452 BC003062 AAH03062 BC010107 AAH10107 BX161519 CAD61952 BX248291 CAD62619 DA044956 DA638578 DA950997 DA991442 DB170842 DQ891835 ABM82761 DQ895021 ABM85947 Y18474 CAB40136 XM_006720302 XP_006720365 XM_011537298 XP_011535600 XM_011537299 XP_011535601 NM_001126105 NP_001119577 NM_001126106 NP_001119578 NR_040448 NM_003982
Function	Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L- arginine in monocytes. {ECO:0000269|PubMed:14603368, ECO:0000269|PubMed:15280038, ECO:0000269|PubMed:17329401, ECO:0000269|PubMed:9829974, ECO:0000269|PubMed:9878049}.
Subcellular Location	Basolateral cell membrane {ECO:0000269|PubMed:15756301}; Multi-pass membrane protein {ECO:0000269|PubMed:15756301}.
Tissue Specificity	Highest expression in kidney and peripheral blood leukocytes. Weaker expression is observed in lung, heart, placenta, spleen, testis and small intestine. Expressed in normal fibroblasts and those from LPI patients. Also expressed in HUVECs, monocytes, retinal pigment epithelial cells, and various carcinoma cell lines, with highest expression in a colon-carcinoma cell line. {ECO:0000269|PubMed:10080183, ECO:0000269|PubMed:11078698, ECO:0000269|PubMed:11742806, ECO:0000269|PubMed:15280038, ECO:0000269|PubMed:17197568, ECO:0000269|PubMed:17329401, ECO:0000269|PubMed:9829974}.
Top Pathways	Protein digestion and absorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SLC7A7 full length protein - ab160316 from Abcam Category Protein Source Wheat germ Species Human

Human SLC7A7 full length protein - ab160317 from Abcam Category Protein Source Wheat germ Species Human

Human SLC7A7 protein fragment - ab160318 from Abcam Category Protein Source Wheat germ Species Human

SLC7A7 Antibody Blocking Peptide - LS-E16125 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SLC7A7 Protein - H00009056-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human SLC7A7 Protein - H00009056-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human SLC7A7 Protein - H00009056-P02 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

SLC7A7-Antibody-C-term-Blocking-Peptide - BP17085b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SLC7A7 Blocking Peptide - 33R-9952 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SLC7A7 - H00009056-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

SLC7A7 - H00009056-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

SLC7A7 - H00009056-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

SLC7A7 - H00009056-P02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

SLC7A7 - H00009056-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SLC7A7 - H00009056-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SLC7A7 fusion protein - Ag23872 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PET30a Species Human

Recombinant L-Type Amino Acid Transporter 1 (y+LAT1) - RPE417Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant L-Type Amino Acid Transporter 1 (y+LAT1) - RPE417Hu01 from Cloud-clone Category Protein Source E.coli Species Human

SLC7A7 Recombinant Protein Antigen - NBP1-82826PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SLC7A7 Peptide, Human - M34GP14650H from Creative Peptides Category Peptide Source Synthetic. Species Human

Search more