ASZ1

Gene Symbol	ASZ1
Entrez Gene	136991
Alt Symbol	ALP1, ANKL1, C7orf7, CT1.19, GASZ, Orf3
Species	Human
Gene Type	protein-coding
Description	ankyrin repeat, SAM and basic leucine zipper domain containing 1
Other Description	ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1|ankyrin-like 1|ankyrin-like protein 1|germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein
Swissprots	B7ZM20 Q8WWH4 A4D0V0 A0AV27
Accessions	CBH19198 CBH30664 EAL24354 EAW83526 EAW83527 EAW83528 Q8WWH4 AF461259 AAL68815 AK093445 BAC04167 BC028695 BC034963 AAH34963 BC068488 BC098399 BC126186 AAI26187 BC126188 AAI26189 BC144207 BC144212 AAI44213 DB457846 HQ258436 ADR83190 XM_011515802 XP_011514104 NR_023315 NM_001301821 NP_001288750 NM_001301822 NP_001288751 NM_130768 NP_570124
Function	Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi- bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity). {ECO:0000250}.
Tissue Specificity	Expressed exclusively in the testis and ovary and at higher levels in the adult testis compared with the adult ovary. {ECO:0000269|PubMed:12040005}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ASZ1 - MBS1265990 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC126186

Human ASZ1 Gene ORF cDNA clone in cloning vector - HG15696-G from Sino Biological Species Human

Human ASZ1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15696-ACR from Sino Biological Species Human

Human ASZ1 Gene ORF cDNA clone expression plasmid, C-His tag - HG15696-CH from Sino Biological Species Human

Human ASZ1 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15696-ANG from Sino Biological Species Human

Human ASZ1 Gene ORF cDNA clone expression plasmid, N-His tag - HG15696-NH from Sino Biological Species Human

Human ASZ1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG15696-CY from Sino Biological Species Human

Human ASZ1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15696-CF from Sino Biological Species Human

Human ASZ1 Gene ORF cDNA clone expression plasmid - HG15696-G-N from Sino Biological Species Human

Human ASZ1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15696-CM from Sino Biological Species Human

Human ASZ1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15696-NM from Sino Biological Species Human

Human ASZ1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15696-ACG from Sino Biological Species Human

Human ASZ1 Gene ORF cDNA clone expression plasmid - HG15696-UT from Sino Biological Species Human

Human ASZ1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG15696-NY from Sino Biological Species Human

Human ASZ1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15696-NF from Sino Biological Species Human

Human ASZ1 ORF Clone (BC126186) - CDCS416708 from Creative biogene Species Human Accession Q8WWH4

Human ASZ1 ORF clone (BC126186) - CDCB157947 from Creative biogene Species Human

Human ASZ1 Gene cDNA Clone - orb141909 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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