ASZ1

Gene Symbol	ASZ1
Entrez Gene	136991
Alt Symbol	ALP1, ANKL1, C7orf7, CT1.19, GASZ, Orf3
Species	Human
Gene Type	protein-coding
Description	ankyrin repeat, SAM and basic leucine zipper domain containing 1
Other Description	ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1|ankyrin-like 1|ankyrin-like protein 1|germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein
Swissprots	B7ZM20 Q8WWH4 A4D0V0 A0AV27
Accessions	CBH19198 CBH30664 EAL24354 EAW83526 EAW83527 EAW83528 Q8WWH4 AF461259 AAL68815 AK093445 BAC04167 BC028695 BC034963 AAH34963 BC068488 BC098399 BC126186 AAI26187 BC126188 AAI26189 BC144207 BC144212 AAI44213 DB457846 HQ258436 ADR83190 XM_011515802 XP_011514104 NR_023315 NM_001301821 NP_001288750 NM_001301822 NP_001288751 NM_130768 NP_570124
Function	Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi- bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity). {ECO:0000250}.
Tissue Specificity	Expressed exclusively in the testis and ovary and at higher levels in the adult testis compared with the adult ovary. {ECO:0000269|PubMed:12040005}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ASZ1 full length protein - ab165403 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human ASZ1 protein fragment - ab165404 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

ASZ1 / Orf3 Antibody Blocking Peptide - LS-E18905 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ASZ1 Protein - H00136991-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ASZ1 Protein - H00136991-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

E.coli ORF3 protein - orb244788 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Escherichia coli

HEV-ORF2/ORF3/2 Mosaic protein - orb97970 from Biorbyt Category Protein Prices $383.00 Sizes 100 μg

HEV-ORF2/ORF3/1 Mosaic protein - orb97969 from Biorbyt Category Protein

HEV-ORF2/ORF3/1 Mosaic protein - orb97968 from Biorbyt Category Protein Prices $383.00, $1,292.00 Sizes 100 μg, 1 mg

ASZ1 Blocking Peptide - 33R-3373 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ASZ1 / ALP1 - H00136991-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ASZ1 / ALP1 - H00136991-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ASZ1 / ALP1 - H00136991-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ASZ1 / ALP1 - H00136991-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ASZ1 fusion protein - Ag16217 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

ASZ1 fusion protein - Ag17055 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human ASZ1, GST-tagged - ASZ1-9953H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Hepatitis E virus genotype 1 Protein ORF3 (ORF3) - CSB-YP527126HVZ CSB-BP527126HVZ CSB-MP527126HVZ from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant Hepatitis E virus genotype 1 Protein ORF3 - CSB-EP527126HVZ from Cusabio Category Protein Source E.coli

Recombinant Torque teno virus Uncharacterized ORF2/4 protein(ORF2/4, ORF3) - CSB-YP852722TEAC CSB-EP852722TEAC CSB-BP852722TEAC CSB-MP852722TEAC from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Ankyrin repeat, SAM and basic leucine zipper domain-containing - CSB-YP845159HU CSB-EP845159HU CSB-BP845159HU CSB-MP845159HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ASZ1 / ALP1 (transcript variant 1) - TP319070 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (ASZ1) , Recombinant Protein - MBS1319578 from MyBioSource Category Protein Prices $2,055.00, $2,055.00, $2,520.00, $2,520.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant HEV Mosaic ORF2/ORF3 - CSI15788A from Cell Science Prices $250.00 Sizes 100 μg

Recombinant HEV Mosaic ORF2/ORF3 - CSI15788B from Cell Science Prices $760.00 Sizes 500 µg

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