MCRS1

Gene Symbol	MCRS1
Entrez Gene	10445
Alt Symbol	ICP22BP, INO80Q, MCRS2, MSP58, P78
Species	Human
Gene Type	protein-coding
Description	microspherule protein 1
Other Description	58 kDa microspherule protein|INO80 complex subunit J|INO80 complex subunit Q|cell cycle-regulated factor (78 kDa)|cell cycle-regulated factor p78
Swissprots	O14742 O75497 Q6VN53 Q96EZ8 Q7Z372
Accessions	CCQ43031 EAW58075 EAW58076 EAW58077 EAW58078 EAW58079 EAW58080 Q96EZ8 AF015308 AAC52086 AF068007 AAC68599 AK308581 AY336730 AAQ84517 BC011794 AAH11794 BX538079 CAD98003 DQ892887 ABM83813 EU176727 ABW03528 HY078747 R66413 XM_005268572 XP_005268629 XM_011537760 XP_011536062 NM_001012300 NP_001012300 NM_001278341 NP_001265270 NM_006337 NP_006328
Function	Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. {ECO:0000269|PubMed:11948183, ECO:0000269|PubMed:15044100, ECO:0000269|PubMed:20018852}.
Subcellular Location	Nucleus. Nucleus, nucleolus. Note=In microspherules in the nucleolus.
Tissue Specificity	Detected in testis, and at lower levels in spleen, thymus, prostate, uterus, small intestine, colon and leukocytes.
Top Pathways	Herpes simplex infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-MCRS1-cDNA-Clone - DC03198 from Abgent, a WuXi AppTec company Prices $623.70 Sizes 10 µg Species Human Accession BC011794

MCRS1 - MBS1266351 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC011794

Human MCRS1 cDNA clone(NM_001012300.1) - CDFH011216 from Creative Biomart Species Human Accession NM_001012300.1

Human MCRS1 cDNA clone(NM_006337.3) - CDFH011217 from Creative Biomart Species Human Accession NM_006337.3

Human MCRS1 ORF Clone(NM_006337.3) - CDCR292615 from Creative Biomart Species Human Accession NM_006337.3

Human MCRS1 ORF Clone(NM_006337.3) - CDCR292616 from Creative Biomart Species Human Accession NM_006337.3

Human MCRS1 ORF Clone(NM_001012300.1) - CDCR341086 from Creative Biomart Species Human Accession NM_001012300.1

Human MCRS1 ORF Clone(NM_001012300.1) - CDCR341087 from Creative Biomart Species Human Accession NM_001012300.1

Human MCRS1 Gene ORF cDNA clone in cloning vector - HG14816-G from Sino Biological Species Human

Human MCRS1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14816-ACG from Sino Biological Species Human

Human MCRS1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14816-NY from Sino Biological Species Human

Human MCRS1 Gene ORF cDNA clone expression plasmid, N-His tag - HG14816-NH from Sino Biological Species Human

Human MCRS1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14816-G-Y from Sino Biological Species Human

Human MCRS1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14816-ACR from Sino Biological Species Human

Human MCRS1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14816-NF from Sino Biological Species Human

Human MCRS1 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14816-ANR from Sino Biological Species Human

Human MCRS1 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14816-ANG from Sino Biological Species Human

Human MCRS1 Gene ORF cDNA clone expression plasmid, C-His tag - HG14816-CH from Sino Biological Species Human

Human MCRS1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14816-CF from Sino Biological Species Human

Human MCRS1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14816-CY from Sino Biological Species Human

Human MCRS1 Gene ORF cDNA clone expression plasmid - HG14816-UT from Sino Biological Species Human

Human MCRS1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14816-CM from Sino Biological Species Human

Human MCRS1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14816-NM from Sino Biological Species Human

Human MCRS1 ORF Clone(NM_006337.3) - CDCR292615 from Creative biogene Species Human

Mouse MCRS1 ORF clone (NM_001012300.1) - CDCL131429 from Creative biogene Species Human

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