MCRS1

Gene Symbol MCRS1
Entrez Gene 10445
Alt Symbol ICP22BP, INO80Q, MCRS2, MSP58, P78
Species Human
Gene Type protein-coding
Description microspherule protein 1
Other Description 58 kDa microspherule protein|INO80 complex subunit J|INO80 complex subunit Q|cell cycle-regulated factor (78 kDa)|cell cycle-regulated factor p78
Swissprots O14742 O75497 Q6VN53 Q96EZ8 Q7Z372
Accessions CCQ43031 EAW58075 EAW58076 EAW58077 EAW58078 EAW58079 EAW58080 Q96EZ8 AF015308 AAC52086 AF068007 AAC68599 AK308581 AY336730 AAQ84517 BC011794 AAH11794 BX538079 CAD98003 DQ892887 ABM83813 EU176727 ABW03528 HY078747 R66413 XM_005268572 XP_005268629 XM_011537760 XP_011536062 NM_001012300 NP_001012300 NM_001278341 NP_001265270 NM_006337 NP_006328
Function Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. {ECO:0000269|PubMed:11948183, ECO:0000269|PubMed:15044100, ECO:0000269|PubMed:20018852}.
Subcellular Location Nucleus. Nucleus, nucleolus. Note=In microspherules in the nucleolus.
Tissue Specificity Detected in testis, and at lower levels in spleen, thymus, prostate, uterus, small intestine, colon and leukocytes.
Top Pathways Herpes simplex infection

Human MCRS1 full length protein - ab132732 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab132732 stained with Coomassie Blue.

MCRS1 / MSP58 Antibody Blocking Peptide - LS-E4532 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human MCRS1 Protein - H00010445-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

MCRS1-Antibody-N-term-Blocking-Peptide - BP16872a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

MCRS1 - H00010445-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

MCRS1 - H00010445-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

MCRS1 fusion protein - Ag1904 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human MCRS1, His-tagged - MCRS1-30186TH from Creative Biomart

Category Protein
Source E. coli

Recombinant Human Microspherule protein 1(MCRS1) - CSB-YP013611HU CSB-EP013611HU CSB-BP013611HU CSB-MP013611HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

MCRS1 Protein - abx164005 from Abbexa

Category Protein
Species Human

MCRS1 Recombinant Protein Antigen - NBP1-81615PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

MCRS1 Peptide, Human - M34GP09327H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Microspherule protein 1 (MCRS1), Recombinant Protein - MBS1402394 from MyBioSource

Category Protein
Prices $1,245.00, $1,245.00, $1,460.00, $1,460.00, $2,025.00, $2,025.00, $2,490.00, $2,490.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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