MCRS1

Gene Symbol MCRS1
Entrez Gene 10445
Alt Symbol ICP22BP, INO80Q, MCRS2, MSP58, P78
Species Human
Gene Type protein-coding
Description microspherule protein 1
Other Description 58 kDa microspherule protein|INO80 complex subunit J|INO80 complex subunit Q|cell cycle-regulated factor (78 kDa)|cell cycle-regulated factor p78
Swissprots O14742 O75497 Q6VN53 Q96EZ8 Q7Z372
Accessions CCQ43031 EAW58075 EAW58076 EAW58077 EAW58078 EAW58079 EAW58080 Q96EZ8 AF015308 AAC52086 AF068007 AAC68599 AK308581 AY336730 AAQ84517 BC011794 AAH11794 BX538079 CAD98003 DQ892887 ABM83813 EU176727 ABW03528 HY078747 R66413 XM_005268572 XP_005268629 XM_011537760 XP_011536062 NM_001012300 NP_001012300 NM_001278341 NP_001265270 NM_006337 NP_006328
Function Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. {ECO:0000269|PubMed:11948183, ECO:0000269|PubMed:15044100, ECO:0000269|PubMed:20018852}.
Subcellular Location Nucleus. Nucleus, nucleolus. Note=In microspherules in the nucleolus.
Tissue Specificity Detected in testis, and at lower levels in spleen, thymus, prostate, uterus, small intestine, colon and leukocytes.
Top Pathways Herpes simplex infection

MSP58 CRISPR/Cas9 KO Plasmid (h) - sc-405688 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSP58 HDR Plasmid (h) - sc-405688-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSP58 Double Nickase Plasmid (h) - sc-405688-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSP58 Double Nickase Plasmid (h2) - sc-405688-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSP58 CRISPR Activation Plasmid (h) - sc-405688-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSP58 CRISPR Activation Plasmid (h2) - sc-405688-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSP58 Lentiviral Activation Particles (h) - sc-405688-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSP58 Lentiviral Activation Particles (h2) - sc-405688-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MSP58 siRNA (h) - sc-75838 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MSP58 shRNA Plasmid (h) - sc-75838-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MSP58 shRNA (h) Lentiviral Particles - sc-75838-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU085481 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN13131 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13131 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02995 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02995

MCRS1 siRNA (Human) - CRH7085 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MCRS1(NM_001012300.1) - SHH182009 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human MCRS1(NM_006337.3) - SHH182045 from Creative biogene

Category siRNA
Species Reactivities Human

MCRS1 shRNA Plasmid (Human) - CHH7085 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MCRS1 miRNA 3'UTR clone - MiUTR1H-06170 from Creative biogene

Species Reactivities Human

MCRS1 miRNA 3'UTR clone - MiUTR1H-06171 from Creative biogene

Species Reactivities Human
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