Gene Symbol | PELI3 |
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Entrez Gene | 246330 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | pellino E3 ubiquitin protein ligase family member 3 |
Other Description | E3 ubiquitin-protein ligase pellino homolog 3|pellino homolog 3|protein pellino homolog 3 |
Swissprots | Q8TED5 Q8N9Q6 Q8TAW7 Q8N3E1 Q8N2H9 |
Accessions | CAF86908 EAW74532 EAW74533 EAW74534 EAW74535 EAW74536 Q8N2H9 AF487456 AAO49465 AF487457 AAO49466 AK074201 BAB85015 AK075253 BAC11499 AK094060 BAC04275 AL834395 CAD39057 BC021256 AAH21256 BC025723 AAH25723 BC127759 AAI27760 BX341733 DA203229 XM_011544884 XP_011543186 NM_001098510 NP_001091980 NM_001243135 NP_001230064 NM_001243136 NP_001230065 NM_145065 NP_659502 |
Function | E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation. {ECO:0000269|PubMed:12874243, ECO:0000269|PubMed:17675297}. |
Tissue Specificity | Highly expressed in brain, heart and testis, and at lower level in kidney, liver, lung, placenta, small intestine, spleen and stomach. Isoform 1 is not expressed in lung. {ECO:0000269|PubMed:12874243}. |
Human PELI3 full length protein - ab132822 from Abcam
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PELI3 protein (His-DHFR tag) - ab127516 from Abcam
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PELI3 / Pellino 3 Antibody Blocking Peptide - LS-E2437 from LifeSpan Bioscience
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PELI3 / Pellino 3 Antibody Blocking Peptide - LS-E19640 from LifeSpan Bioscience
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PELI3 / Pellino 3 Antibody Blocking Peptide - LS-E19639 from LifeSpan Bioscience
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Recombinant Human PELI3 Protein - H00246330-P01 from Novus Biologicals
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PELI3-Antibody-N-term-Blocking-peptide - BP13453a from Abgent, a WuXi AppTec company
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PELI3 Blocking Peptide - 33R-9649 from Fitzgerald
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PELI3 Blocking Peptide - 33R-9650 from Fitzgerald
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PELI3 - H00246330-P01-10 from Acris Antibodies
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PELI3 - H00246330-P01-25 from Acris Antibodies
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Recombinant Human E3 ubiquitin-protein ligase pellino homolog 3(PELI3) - CSB-YP847618HU CSB-EP847618HU CSB-BP847618HU CSB-MP847618HU from Cusabio
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PELI3 (transcript variant 1) - TP318104 from Acris Antibodies
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PELI3 Recombinant Protein Antigen - NBP2-37889PEP from Novus Biologicals
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PELI3 Recombinant Protein Antigen - NBP2-37988PEP from Novus Biologicals
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PELI3 Peptide, Human - M34GP11585H from Creative Peptides
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E3 ubiquitin-protein ligase pellino homolog 3 (PELI3), Recombinant Protein - MBS1306047 from MyBioSource
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