Gene Symbol | PELI3 |
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Entrez Gene | 246330 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | pellino E3 ubiquitin protein ligase family member 3 |
Other Description | E3 ubiquitin-protein ligase pellino homolog 3|pellino homolog 3|protein pellino homolog 3 |
Swissprots | Q8TED5 Q8N9Q6 Q8TAW7 Q8N3E1 Q8N2H9 |
Accessions | CAF86908 EAW74532 EAW74533 EAW74534 EAW74535 EAW74536 Q8N2H9 AF487456 AAO49465 AF487457 AAO49466 AK074201 BAB85015 AK075253 BAC11499 AK094060 BAC04275 AL834395 CAD39057 BC021256 AAH21256 BC025723 AAH25723 BC127759 AAI27760 BX341733 DA203229 XM_011544884 XP_011543186 NM_001098510 NP_001091980 NM_001243135 NP_001230064 NM_001243136 NP_001230065 NM_145065 NP_659502 |
Function | E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation. {ECO:0000269|PubMed:12874243, ECO:0000269|PubMed:17675297}. |
Tissue Specificity | Highly expressed in brain, heart and testis, and at lower level in kidney, liver, lung, placenta, small intestine, spleen and stomach. Isoform 1 is not expressed in lung. {ECO:0000269|PubMed:12874243}. |
Pellino 3 (B-3) - sc-376466 from Santa Cruz Biotechnology
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Pellino 3 (H-180) - sc-67026 from Santa Cruz Biotechnology
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Pellino 3 (K-14) - sc-31622 from Santa Cruz Biotechnology
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Anti-PELI3 antibody - ab113487 from Abcam
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Anti-PELI3 antibody - ab76034 from Abcam
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Anti-PELI3 antibody - ab116681 from Abcam
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Anti-PELI3 antibody - ab72671 from Abcam
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Anti-PELI3 / Pellino 3 Antibody (aa1-30, AP) - LS-C238917 from LifeSpan Bioscience
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Anti-PELI3 / Pellino 3 Antibody (aa1-30, Biotin) - LS-C238919 from LifeSpan Bioscience
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Anti-PELI3 / Pellino 3 Antibody (aa1-30, FITC) - LS-C238918 from LifeSpan Bioscience
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Anti-PELI3 / Pellino 3 Antibody (aa1-30, APC) - LS-C238920 from LifeSpan Bioscience
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Anti-PELI3 / Pellino 3 Antibody (aa1-30, PE) - LS-C238921 from LifeSpan Bioscience
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Anti-PELI3 / Pellino 3 Antibody (aa1-30, Azide-free, HRP) - LS-C248449 from LifeSpan Bioscience
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Anti-PELI3 / Pellino 3 Antibody (aa1-30) - LS-C329960 from LifeSpan Bioscience
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Anti-PELI3 / Pellino 3 Antibody (N-Terminus) - LS-C82790 from LifeSpan Bioscience
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Anti-PELI3 / Pellino 3 Antibody (N-Terminus) - LS-C82791 from LifeSpan Bioscience
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Anti-PELI3 / Pellino 3 Antibody (aa1-30) - LS-C163516 from LifeSpan Bioscience
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Anti-PELI3 / Pellino 3 Antibody (aa52-299) - LS-C178512 from LifeSpan Bioscience
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PELI3 Antibody - NBP1-56410 from Novus Biologicals
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PELI3 Antibody - NBP2-37988 from Novus Biologicals
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PELI3 Antibody - NBP2-37889 from Novus Biologicals
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PELI3 Antibody - H00246330-B01 from Novus Biologicals
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Anti-PELI3 (AB1) antibody produced in rabbit - AV54532 from Sigma-Aldrich
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ANTI-PELI3(N-TERMINAL) antibody produced in rabbit - SAB1306956 from Sigma-Aldrich
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Anti-PELI3 (AB2) antibody produced in rabbit - AV54533 from Sigma-Aldrich
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