FUT3

Gene Symbol	FUT3
Entrez Gene	2525
Alt Symbol	CD174, FT3B, FucT-III, LE, Les
Species	Human
Gene Type	protein-coding
Description	fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
Other Description	Lewis FT|alpha-(1,3/1,4)-fucosyltransferase|blood group Lewis alpha-4-fucosyltransferase|fucosyltransferase III|galactoside 3(4)-L-fucosyltransferase
Swissprots	Q99449 P21217 Q99448 B5U7V0 B5U7U9 Q32NE7
Accessions	AAW34365 BAA13941 BAA13942 BAA96390 CAQ56302 CAQ68512 CAQ68513 CAQ68514 CAQ81986 CAQ81987 CAR64692 CAR64693 EAW69135 P21217 AF131913 AAD33514 AK291852 BAF84541 AK313575 BAG36347 BC074836 AAH74836 BC074837 AAH74837 BC108675 AAI08676 BM671165 DA876997 DA930897 DB200655 U27326 AAC50185 U27327 AAC50186 U27328 AAC50187 X53578 CAA37641 XM_011527865 XP_011526167 XM_011527866 XP_011526168 XM_011527867 XP_011526169 NM_000149 NP_000140 NM_001097639 NP_001091108 NM_001097640 NP_001091109 NM_001097641 NP_001091110
Function	May catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of Vim-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. May be involved in blood group Lewis determination; Lewis-positive (Le(+)) individuals have an active enzyme while Lewis-negative (Le(-)) individuals have an inactive enzyme. Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L-fucosyl links.
Subcellular Location	Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Tissue Specificity	Highly expressed in stomach, colon, small intestine, lung and kidney and to a lesser extent in salivary gland, bladder, uterus and liver.
Top Pathways	Glycosphingolipid biosynthesis - lacto and neolacto series

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FUT3 293T Cell Transient Overexpression Lysate(Denatured) - H00002525-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

FUT3 293 Cell Lysate - 410319 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg Tissue Blood

Blood Group Lewis b Overexpression Lysate (Denatured) - H00002525-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl Tissue Blood

Blood Group Lewis b Overexpression Lysate (Native) - NBL1-10865 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg Tissue Blood

FUT3 Over-expression Lysate Product - GWB-443C55 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Lewis A Blood Group Antigen Overexpression Lysate (Native) - NBP2-11433 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg Tissue Blood

Lewis A Blood Group Antigen Overexpression Lysate (Native) - NBP2-11432 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg Tissue Blood

Lewis A Blood Group Antigen Overexpression Lysate (Native) - NBP2-11431 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg Tissue Blood

Lewis A Blood Group Antigen Overexpression Lysate (Native) - NBP2-10936 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg Tissue Blood

Lewis A Blood Group Antigen Overexpression Lysate (Native) - NBP2-10935 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg Tissue Blood

Lewis A Blood Group Antigen Overexpression Lysate (Native) - NBP2-10934 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg Tissue Blood

Panoply™ Human FUT3 Knockdown Stable Cell Line - CSC-DC005961 from Creative biogene Category Cell Line Species Human

Search more