FUT3

Gene Symbol	FUT3
Entrez Gene	2525
Alt Symbol	CD174, FT3B, FucT-III, LE, Les
Species	Human
Gene Type	protein-coding
Description	fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
Other Description	Lewis FT|alpha-(1,3/1,4)-fucosyltransferase|blood group Lewis alpha-4-fucosyltransferase|fucosyltransferase III|galactoside 3(4)-L-fucosyltransferase
Swissprots	Q99449 P21217 Q99448 B5U7V0 B5U7U9 Q32NE7
Accessions	AAW34365 BAA13941 BAA13942 BAA96390 CAQ56302 CAQ68512 CAQ68513 CAQ68514 CAQ81986 CAQ81987 CAR64692 CAR64693 EAW69135 P21217 AF131913 AAD33514 AK291852 BAF84541 AK313575 BAG36347 BC074836 AAH74836 BC074837 AAH74837 BC108675 AAI08676 BM671165 DA876997 DA930897 DB200655 U27326 AAC50185 U27327 AAC50186 U27328 AAC50187 X53578 CAA37641 XM_011527865 XP_011526167 XM_011527866 XP_011526168 XM_011527867 XP_011526169 NM_000149 NP_000140 NM_001097639 NP_001091108 NM_001097640 NP_001091109 NM_001097641 NP_001091110
Function	May catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of Vim-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. May be involved in blood group Lewis determination; Lewis-positive (Le(+)) individuals have an active enzyme while Lewis-negative (Le(-)) individuals have an inactive enzyme. Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L-fucosyl links.
Subcellular Location	Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Tissue Specificity	Highly expressed in stomach, colon, small intestine, lung and kidney and to a lesser extent in salivary gland, bladder, uterus and liver.
Top Pathways	Glycosphingolipid biosynthesis - lacto and neolacto series

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FUT3 full length protein - ab152401 from Abcam Category Protein Source Wheat germ Species Human

Human FUT3 protein fragment - ab114431 from Abcam Category Protein Source Wheat germ Species Human

Human FUT3 protein fragment - ab171721 from Abcam Category Protein Source E. coli Species Human

FUT3 / CD174 Antibody Blocking Peptide - LS-E23319 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FUT3 / CD174 Antibody Blocking Peptide - LS-E23320 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FUT3 / CD174 Antibody Blocking Peptide - LS-E10115 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Blood Group Lewis b Protein - H00002525-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Blood Group Lewis b Protein - H00002525-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human Lewis A Blood Group Antigen Protein - NBP2-23063 from Novus Biologicals Category Protein Prices $269.00 Sizes 50 µg Source E.coli Species Human

FUT3-Antibody-C-term-Blocking-Peptide - BP9410b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Fucosyltransferase 3/FUT3, CF - 4950-GT-020 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Arg35-Thr361, with an N-terminal 6-His tag

FUT3 peptide - orb217310 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

FUT3 protein (His tag) - 80R-3028 from Fitzgerald Category Protein Prices $275.00 Sizes 50 µg Source E.coli

CD174 Blocking Peptide - abx062641 from Abbexa Category Peptide Species Human, Mouse, Rat

Human CA19-9 Protein - abx065680 from Abbexa Category Protein Source E.coli Species Human

Fucosyltransferase 3 (35-361, His-tag) - AR51146PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

Fucosyltransferase 3 (35-361, His-tag) - AR51146PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

Fucosyltransferase 3 - H00002525-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

Fucosyltransferase 3 - H00002525-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Fucosyltransferase 3 - H00002525-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Carbohydrate Antigen 19-9 (CA19-9), Human - 20-6373 from ARP American Research Products Category Protein Prices $649.00 Sizes 50 µg Source E.coli Species Human

FUT3, 35-361aa, Human, His tag, E.coli - 01-P2322 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

FUT3 fusion protein - ag12140 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

FUT3 fusion protein - Ag12581 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human Fucosyltransferase 3 (galactoside 3 (4)-L-fucosyltransferase, Lewis blood group), His-tagged - FUT3-573H from Creative Biomart Category Protein Source Murine myeloma cellline, NS0-derived

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