FLII

Gene Symbol FLII
Entrez Gene 2314
Alt Symbol FLI, FLIL, Fli1
Species Human
Gene Type protein-coding
Description flightless I homolog (Drosophila)
Other Description protein flightless-1 homolog
Swissprots F5H407 B4DIL0 J3QLG3 Q13045
Accessions AAC02796 EAW55653 EAW55654 EAW55655 EAW55656 Q13045 AB208864 BAD92101 AK295655 BAG58522 AK295814 BAG58632 AK297836 BAG60170 AK310400 BC001582 BC017030 BC021885 BC025300 AAH25300 BM930929 DC341570 DQ893621 ABM84547 DQ896850 ABM87849 U01184 AAC03568 XM_005256555 XP_005256612 XM_005256556 XP_005256613 XM_005256558 XP_005256615 NM_001256264 NP_001243193 NM_001256265 NP_001243194 NM_002018 NP_002009
Function May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling. Involved in early embryonic development (By similarity). May play a role in regulation of cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation. {ECO:0000250, ECO:0000269|PubMed:14966289}.
Subcellular Location Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cell junction, focal adhesion {ECO:0000250}. Note=Colocalizes to actin-rich structures in blastocysts and, together with HRAS, RHOA and CDC42, in migrating fibroblasts. Localizes to centrosomes (By similarity). {ECO:0000250}.
Tissue Specificity Strongest expression in skeletal muscle with high expression also in the heart and lung. {ECO:0000269|PubMed:9525888}.

Flightless-I Antibody - 14189 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using Flightless-I Antibody.

Flightless I (B-6) - sc-377029 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Flightless I (B-6): sc-377029. Western blot analysis of Flightless I expression in non-transfected 293T: sc-117752 (A), mouse Flightless I transfected 293T: sc-125338 (B) and SJRH30 (C) whole cell lysates.

Flightless I (E-1) - sc-55583 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Flightless I (E-1): sc-55583. Western blot analysis of Flightless I expression in C32 (A), SJRH30 (B), Sol8 (C) and L8 (D) whole cell lysates.

Flightless I (G-18) - sc-31122 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Flightless I (G-18): sc-31122. Western blot analysis of Flightless I expression in SJRH30 whole cell lysate.

Flightless I (I-19) - sc-31121 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Flightless I (H-300) - sc-30046 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Flightless I (H-300): sc-30046. Western blot analysis of Flightless I expression in Sol8 (A) and L8 (B) whole cell lysates.

Flightless I (N-20) - sc-22123 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Flightless I (N-20): sc-22123. Western blot analysis of Flightless I expression in L6 (A) and SJRH30 (B) whole cell lysates, mouse heart tissue extract (C) and NIH/3T3 nuclear extract (D).

Flightless I (116.40) - sc-21716 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Flightless I (116.40): sc-21716. Western blot analysis of Flightless I expression in C32 (A), Sol8 (B) and L8 (C) whole cell lysates.

Anti-Flightless I antibody - ab176805 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Flightless I antibody (ab176805) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-Flightless I antibody - ab96314 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Flightless I antibody (ab96314) at 1/1000 dilution + Raji whole cell lysate at 30 µg

Anti-Flightless I antibody - ab84778 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human prostate carcinoma, using 1/100 ab84778 in conjunction with 1/100 Goat anti-Rabbit IgG secondary antibody conjugated to a fluorescent dye (red).

Anti-Flightless I antibody [116.40] - ab28089 from Abcam

Prices $372.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 116.40

Anti-Flightless I antibody [EPR4201] - ab108594 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4201
All lanes : Anti-Flightless I antibody [EPR4201] (ab108594) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : A549 cell lysateLane 3 : A431 cell lysateLysates/proteins at 10 µg per lane.

Anti-Flightless I antibody [EPR4202(2)] - ab109015 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4202(2)
All lanes : Anti-Flightless I antibody [EPR4202(2)] (ab109015) at 1/1000 dilutionLane 1 : Humam heart lysateLane 2 : HeLa lysateLane 3 : A431 lysateLane 4 : A549 lysateLysates/proteins at 10 µg per lane.

Anti-FLII / FLI Antibody (aa1224-1240) - LS-C149025 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-FLII / FLI Antibody (FITC) - LS-C317883 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FLII / FLI Antibody (HRP) - LS-C317884 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FLII / FLI Antibody - LS-C317885 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FLII / FLI Antibody (Biotin) - LS-C318967 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FLII / FLI Antibody (aa1116-1165) IHC-plus™ - LS-B10888 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human, Prostate: Formalin-Fixed Paraffin-Embedded (FFPE)

Anti-FLII / FLI Antibody (aa90-140) IHC-plus™ - LS-B7992 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-FLII / FLI antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7992 dilution 5-10 ug/ml.

Anti-FLII / FLI Antibody (aa425-475) - LS-C288363 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human Flightless-1 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-Flightless-1 used at a dilution of 1:200 (1 Detection: DAB.

Anti-FLII / FLI Antibody (Internal, clone EPR4202(2)) - LS-C138339 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4202(2)
IHC of paraffin-embedded human muscle tissue using anti-Flightless 1 antibody.

Anti-FLII / FLI Antibody (Internal, clone EPR4201) - LS-C137780 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4201
IHC of paraffin-embedded human skeletal muscle tissue using anti-Flightless 1 antibody.

Anti-FLII / FLI Antibody (aa425-475) - LS-C286578 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human Flightless-1 by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-Flightless-1 used at a dilution of 1:250.
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