FLII

Gene Symbol	FLII
Entrez Gene	2314
Alt Symbol	FLI, FLIL, Fli1
Species	Human
Gene Type	protein-coding
Description	flightless I homolog (Drosophila)
Other Description	protein flightless-1 homolog
Swissprots	F5H407 B4DIL0 J3QLG3 Q13045
Accessions	AAC02796 EAW55653 EAW55654 EAW55655 EAW55656 Q13045 AB208864 BAD92101 AK295655 BAG58522 AK295814 BAG58632 AK297836 BAG60170 AK310400 BC001582 BC017030 BC021885 BC025300 AAH25300 BM930929 DC341570 DQ893621 ABM84547 DQ896850 ABM87849 U01184 AAC03568 XM_005256555 XP_005256612 XM_005256556 XP_005256613 XM_005256558 XP_005256615 NM_001256264 NP_001243193 NM_001256265 NP_001243194 NM_002018 NP_002009
Function	May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling. Involved in early embryonic development (By similarity). May play a role in regulation of cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation. {ECO:0000250, ECO:0000269|PubMed:14966289}.
Subcellular Location	Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cell junction, focal adhesion {ECO:0000250}. Note=Colocalizes to actin-rich structures in blastocysts and, together with HRAS, RHOA and CDC42, in migrating fibroblasts. Localizes to centrosomes (By similarity). {ECO:0000250}.
Tissue Specificity	Strongest expression in skeletal muscle with high expression also in the heart and lung. {ECO:0000269|PubMed:9525888}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FLII / FLI Antibody Blocking Peptide - LS-E19674 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FLII Blocking Peptide - 33R-4761 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FLII fusion protein - ag2240 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Flightless I Homolog (FLII) - RPJ932Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Flightless I Homolog (FLII) - RPJ932Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Protein flightless-1 homolog(FLII) ,partial - CSB-YP615661HU CSB-EP615661HU CSB-BP615661HU CSB-MP615661HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Flightless I Recombinant Protein Antigen - NBP1-87926PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Flightless I Recombinant Protein Antigen - NBP1-87925PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

FLII Peptide, Human - M34GP05778H from Creative Peptides Category Peptide Source Synthetic. Species Human

Flightless I Homolog, Recombinant Protein - MBS2030351 from MyBioSource Category Protein Prices $185.00, $380.00, $585.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

FLII fusion protein - Ag26865 from Proteintech Group Category Protein Source E. coli -derived, PET30a Species Human

FLII Recombinant Protein (OPCD03262) - OPCD03262 from Aviva Systems Biology Category Protein Source E.coli Species Human

Protein flightless-1 homolog (FLII), partial, Recombinant Protein - MBS1422569 from MyBioSource Category Protein Prices $870.00, $870.00, $1,090.00, $1,090.00, $1,170.00, $1,170.00, $1,690.00, $1,690.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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