WDR34

Gene Symbol	WDR34
Entrez Gene	89891
Alt Symbol	DIC5, FAP133, SRTD11, bA216B9.3
Species	Human
Gene Type	protein-coding
Description	WD repeat domain 34
Other Description	WD repeat-containing protein 34
Swissprots	Q9BV46 Q96EX3 Q5VXV4
Accessions	EAW87814 EAW87815 EAW87816 Q96EX3 AK302098 BAG63480 AL555205 BC001614 AAH01614 BC011874 AAH11874 BG177634 BI910783 XM_011519179 XP_011517481 NM_052844 NP_443076
Function	Critical for ciliary functions, essential to normal development and survival, most probably as a previously unrecognized component of the mammalian dynein-motor-based intraflagellar transport (IFT) machinery. Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Inhibits the MAP3K7-induced NF-kappa-B activation pathway. Inhibits MAP3K7 phosphorylation at 'Thr-184' and 'Thr-187' upon Il-1 beta stimulation. {ECO:0000269|PubMed:19521662, ECO:0000269|PubMed:24183449}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:19521662}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:19521662}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:19521662}. Note=Concentrates around the centrioles and basal bodies also showing axonemal staining. {ECO:0000250}.
Tissue Specificity	Expressed in several cell lines (at protein level). {ECO:0000269|PubMed:19521662}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human WDR34 full length protein - ab164799 from Abcam Category Protein Source Wheat germ Species Human

WDR34 Antibody Blocking Peptide - LS-E1660 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

WDR34 Antibody Blocking Peptide - LS-E17518 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human WDR34 Protein - H00089891-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

WDR34-Antibody-Center-Blocking-peptide - BP12421c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

WDR34 Blocking Peptide - 33R-8605 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

WDR34 - H00089891-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

Recombinant Human WD repeat-containing protein 34(WDR34) - CSB-YP842668HU CSB-EP842668HU CSB-BP842668HU CSB-MP842668HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

WDR34 - TP304288 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

WD repeat-containing protein 34 (WDR34) , Recombinant Protein - MBS1289912 from MyBioSource Category Protein Prices $2,195.00, $2,195.00, $2,660.00, $2,660.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

WDR34 Recombinant Protein Antigen - NBP1-88806PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

WDR34 Recombinant Protein Antigen - NBP1-88805PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

WDR34 Peptide, Human - M34GP17416H from Creative Peptides Category Peptide Source Synthetic. Species Human

WDR34 fusion protein - Ag23853 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

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