WDR34

Gene Symbol WDR34
Entrez Gene 89891
Alt Symbol DIC5, FAP133, SRTD11, bA216B9.3
Species Human
Gene Type protein-coding
Description WD repeat domain 34
Other Description WD repeat-containing protein 34
Swissprots Q9BV46 Q96EX3 Q5VXV4
Accessions EAW87814 EAW87815 EAW87816 Q96EX3 AK302098 BAG63480 AL555205 BC001614 AAH01614 BC011874 AAH11874 BG177634 BI910783 XM_011519179 XP_011517481 NM_052844 NP_443076
Function Critical for ciliary functions, essential to normal development and survival, most probably as a previously unrecognized component of the mammalian dynein-motor-based intraflagellar transport (IFT) machinery. Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Inhibits the MAP3K7-induced NF-kappa-B activation pathway. Inhibits MAP3K7 phosphorylation at 'Thr-184' and 'Thr-187' upon Il-1 beta stimulation. {ECO:0000269|PubMed:19521662, ECO:0000269|PubMed:24183449}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:19521662}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:19521662}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:19521662}. Note=Concentrates around the centrioles and basal bodies also showing axonemal staining. {ECO:0000250}.
Tissue Specificity Expressed in several cell lines (at protein level). {ECO:0000269|PubMed:19521662}.

WDR34 CRISPR/Cas9 KO Plasmid (h) - sc-413811 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

WDR34 HDR Plasmid (h) - sc-413811-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WDR34 Double Nickase Plasmid (h) - sc-413811-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WDR34 Double Nickase Plasmid (h2) - sc-413811-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WDR34 CRISPR Activation Plasmid (h) - sc-413811-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

WDR34 CRISPR Activation Plasmid (h2) - sc-413811-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

WDR34 Lentiviral Activation Particles (h) - sc-413811-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WDR34 Lentiviral Activation Particles (h2) - sc-413811-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

WDR34 siRNA (h) - sc-92913 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

WDR34 shRNA Plasmid (h) - sc-92913-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

WDR34 shRNA (h) Lentiviral Particles - sc-92913-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU136551 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22819 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22819 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

WDR34 siRNA (Human) - CRJ3884 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

WDR34 - MBS8209493 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human WDR34 (NM_052844.3) - SHH446084 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human WDR34(NM_052844.3) - SHL123274 from Creative biogene

Category siRNA
Species Reactivities Human

WDR34 shRNA Plasmid (Human) - CHJ3884 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

WDR34 miRNA 3'UTR clone - MiUTR1H-11209 from Creative biogene

Species Reactivities Human
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