SEMA5A

Gene Symbol	SEMA5A
Entrez Gene	9037
Alt Symbol	SEMAF, semF
Species	Human
Gene Type	protein-coding
Description	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
Other Description	sema F|semaphorin 5A|semaphorin F|semaphorin-5A|semaphorin-F
Swissprots	D3DTC6 O60408 Q13591 Q1RLL9
Accessions	AAC14668 EAX08078 EAX08079 Q13591 AF009314 AF056434 AK022877 AK293441 BAG56944 AK307587 BC115696 AAI15697 BM669539 CX788776 DA336109 KJ534937 AHW56577 KJ535077 AHW56716 U52840 AAC09473 XM_006714506 XP_006714569 XM_006714507 XP_006714570 XM_011514155 XP_011512457 XM_011514156 XP_011512458 XM_011514157 XP_011512459 XM_011514158 XP_011512460 XM_011514159 XP_011512461 NM_003966 NP_003957
Function	Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs) (By similarity). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis. {ECO:0000250, ECO:0000269|PubMed:15218527, ECO:0000269|PubMed:19850054, ECO:0000269|PubMed:20696765, ECO:0000269|PubMed:21706053}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SEMA5A / Semaphorin 5A ELISA Kit (Sandwich ELISA) - LS-F8175 from LifeSpan Bioscience Category ELISA Kit Prices $790.00 Sizes 1 plate Sensitivity 0.27 ng/ml Range 0.781-50 ng/ml

Semaphorin 5A (SEMA5A), Human, ELISA Kit - SEL924Hu from ARP American Research Products Category ELISA Kit Prices $790.00 Sizes 96 t Sensitivity 0.27ng/mL Range 0.78 -50ng/mL

Semaphorin-5A, SEMA5A, Human, ELISA Kit - E1512h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

Semaphorin 5A, ELISA Kit - MBS065626 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Semaphorin 5A, ELISA Kit - MBS088183 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Semaphorin 5A, ELISA Kit - MBS062073 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Semaphorin 5A, ELISA Kit - MBS077950 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Semaphorin 5A, ELISA Kit - MBS073118 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Semaphorin 5A, ELISA Kit - MBS082127 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Semaphorin 5A, ELISA Kit - MBS104158 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Semaphorin 5A (SEMA5A), ELISA Kit - MBS2019755 from MyBioSource Category ELISA Kit Prices $410.00, $610.00, $830.00, $3,420.00, $6,200.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.31ng/mL. Range 0.78-50ng/mL.

ELISA Kit for Semaphorin 5A (SEMA5A) - SEL924Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.27ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA’s were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

ELISA Kit for Semaphorin 5A (SEMA5A) - SEL924Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.27ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA's were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Human SEMA5A / Semaphorin 5A ELISA Kit (Custom ELISA) - LS-F17876 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.781-50 ng/ml

Mouse SEMA5A / Semaphorin 5A ELISA Kit (Custom ELISA) - LS-F17877 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.781-50 ng/ml

Human Semaphorin 5A (SEMA5A) ELISA Kit - EKU07268 from Biomatik Category ELISA Kit Prices $809.00, $3,557.00, $6,468.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.27 ng/mL Range 0.781-50 ng/mL

Human Semaphorin 5A ELISA Kit - abx153053 from Abbexa Category ELISA Kit Sensitivity 0.27 ng/ml Range 0.781 ng/ml - 50 ng/ml

Human Semaphorin-5A ELISA Kit - abx251082 from Abbexa Category ELISA Kit Range 0.312 ng/ml - 20 ng/ml

Semaphorin 5A (SEMA5A), Human, ELISA Kit - DL-SEMA5A-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.78 -50 ng/mL

Human SEMA5A ELISA Kit - abx573582 from Abbexa Category ELISA Kit Sensitivity 0.27 ng/ml Range 0.781 ng/ml - 50 ng/ml

Human Semaphorin-5A ELISA Kit - EKE53294 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.156 ng/mL Range 0.312-20 ng/mL

SEMA5A - EKH3552 from Nordic BioSite Sensitivity 0.188ng/ml Range 0.312-20ng/ml

Custom Human Semaphorin 5A ELISA - ELH-SEMA5A-1 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Custom Human Semaphorin 5A ELISA Kit - orb384785 from Biorbyt Category ELISA Kit Prices $1,411.00, $2,448.00, $5,321.00 Sizes 96 assays, 192 assays, 480 assays

Human SEMA5A ELISA Kit - E034608 from Biobool Category ELISA Kit Sensitivity Typically less than 0.27ng/mL.

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