PRKCD

Gene Symbol	PRKCD
Entrez Gene	5580
Alt Symbol	ALPS3, CVID9, MAY1, PKCD, nPKC-delta
Species	Human
Gene Type	protein-coding
Description	protein kinase C, delta
Other Description	protein kinase C delta VIII|protein kinase C delta type|tyrosine-protein kinase PRKCD
Swissprots	B0KZ81 Q86XJ6 Q05655 Q15144 B2R834
Accessions	CAV30705 EAW65279 EAW65280 Q05655 AK130150 AK131548 AK294272 BAG57562 AK313216 BAG36031 AW293041 BC043350 AAH43350 BC127261 BE048101 CD369320 D10495 BAA01381 DQ516383 ABF68960 L07860 AAA03176 L07861 AAA03175 Z22521 CAA80249 XM_006713257 XP_006713320 XM_006713258 XP_006713321 XM_006713259 XP_006713322 XR_940474 NM_006254 NP_006245 NM_212539 NP_997704
Function	Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor- initiated cell death, is involved in tumor suppression as well as survival of several cancers, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses. Negatively regulates B cell proliferation and also has an important function in self- antigen induced B cell tolerance induction. Upon DNA damage, activates the promoter of the death-promoting transcription factor BCLAF1/Btf to trigger BCLAF1-mediated p53/TP53 gene transcription and apoptosis. In response to oxidative stress, interact with and activate CHUK/IKKA in the nucleus, causing the phosphorylation of p53/TP53. In the case of ER stress or DNA damage-
Subcellular Location	Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Endoplasmic reticulum. Mitochondrion. Cell membrane; Peripheral membrane protein.
Top Pathways	Neurotrophin signaling pathway, Tight junction, Fc gamma R-mediated phagocytosis, Type II diabetes mellitus, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse PRKCD / PKC-Delta ELISA Kit (Sandwich ELISA) - LS-F5851 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 0.54 ng/ml Range 1.56 - 100 ng/ml

Mouse/Human/Rat Phospho-PRKCD / PKC-Delta (Tyr52) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1302 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

Mouse/Human/Rat Phospho-PRKCD / PKC-Delta (Thr505) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1274 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

Mouse/Human/Rat Phospho-PRKCD / PKC-Delta (Tyr313) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1275 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

Mouse/Human/Rat Phospho-PRKCD / PKC-Delta (Tyr64) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1697 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

Human Phospho-PRKCD / PKC-Delta (Ser645) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1603 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

Mouse/Human/Rat PRKCD / PKC-Delta ELISA Kit (Cell-Based ELISA) - LS-F2249 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate

Human PRKCD / PKC-Delta ELISA Kit (Sandwich ELISA) - LS-F9277 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.059 ng/ml Range 0.156 - 10 ng/ml

Rat PRKCD / PKC-Delta ELISA Kit (Sandwich ELISA) - LS-F9666 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.053 ng/ml Range 0.156 - 10 ng/ml

Human PKCd ELISA Kit - abx152753 from Abbexa Category ELISA Kit Sensitivity 0.059 ng/ml Range 0.156 ng/ml - 10 ng/ml

Protein Kinase C Delta (PKCd), Human, ELISA Kit - SEA433Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.059ng/mL Range 0.156-10ng/mL

Protein Kinase C Delta, PKCd, Mouse, ELISA Kit - E-EL-M0974 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Protein Kinase C Delta, PKCD, Rat, ELISA Kit - E-EL-R0809 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

Human PKCd ELISA Kit - HP0110 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine PKCd ELISA Kit - AP0110 from NeoScientific Category ELISA Kit Prices $380.00, $620.00 Sizes 100 µl, 200 µl

PKC delta Colorimetric Cell-Based ELISA Kit - CB5563 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

PKC delta (Phospho-Thr505) Colorimetric Cell-Based ELISA Kit - CBP1275 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

PKC delta (Phospho-Tyr313) Colorimetric Cell-Based ELISA Kit - CBP1276 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

PKC delta (Phospho-Tyr52) Colorimetric Cell-Based ELISA Kit - CBP1306 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

PKC delta (Phospho-Ser645) Colorimetric Cell-Based ELISA Kit - CBP1657 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

PKC delta (Phospho-Tyr64) Colorimetric Cell-Based ELISA Kit - CBP1767 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

ELISA Kit for Protein Kinase C Delta (PKCd) - SEA433Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.059ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Protein Kinase C Delta (PKCd) - SEA433Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.54ng/mL. Range 1.56-100ng/mL The standard curve concentrations used for the ELISA’s were 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.13ng/mL, 1.56ng/mL

ELISA Kit for Protein Kinase C Delta (PKCd) - SEA433Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.053ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

PKCD, ELISA Kit - MBS2502913 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.938ng/mL Range 1.563--100ng/mL

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