PLCB1

Gene Symbol PLCB1
Entrez Gene 23236
Alt Symbol EIEE12, PI-PLC, PLC-154, PLC-I, PLC154, PLCB1A, PLCB1B
Species Human
Gene Type protein-coding
Description phospholipase C, beta 1 (phosphoinositide-specific)
Other Description 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate|1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1|PLC-beta-1|inositoltrisphosphohydrolase|monophosphatidylinositol phosphodiesterase|phosphoinositidase C|phospholipase C-I|triphosphoinositide phosphodiesterase
Swissprots Q9NTH4 Q9H8H5 Q5TGC9 Q8IV93 Q17RQ6 Q9NQH9 Q9H4H2 Q9BQW2 Q9UJP6 D3DW12 O60325 Q5TFF7 Q9NQ65 D3DW13 Q9NQ66 Q9UM26
Accessions CBF62960 CBF74720 CBU87836 CBU96783 EAX10372 EAX10373 EAX10374 EAX10375 EAX10376 Q9NQ66 AB011153 BAA25507 AJ278313 CAB98142 AJ278314 CAB98143 AK023689 BAB14641 AK127693 BAG54550 AK299195 BAG61238 AK310597 AL137267 CAB70666 AY004175 AAF86613 BC069420 AAH69420 BC117231 AAI17232 BQ184058 HQ258537 ADR83291 XM_011529199 XP_011527501 XM_011529200 XP_011527502 XM_011529201 XP_011527503 XM_011529202 XP_011527504 XM_011529203 XP_011527505 NM_015192 NP_056007 NM_182734 NP_877398
Function The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Subcellular Location Nucleus membrane {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes. {ECO:0000250}.
Top Pathways Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway, Thyroid hormone synthesis, Estrogen signaling pathway, Inflammatory mediator regulation of TRP channels

Human Phospholipase C beta 1 protein fragment - ab153213 from Abcam

Category Protein
Source Wheat germ
Species Human
ab153213 on a 12.5% SDS-PAGE stained with Coomassie Blue.

PLCB1 / Phospholipase C Beta 1 Antibody Blocking Peptide - LS-E10092 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human PLC-beta 1 Protein - H00023236-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

PLCB1-Antibody-C-term-Blocking-Peptide - BP9374b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

PLCB1 Blocking Peptide - 33R-2278 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

PLCB1 - H00023236-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

PLCB1 - H00023236-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

PLCB1 fusion protein - Ag24750 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human PLCB1 - PLCB1-831H from Creative Biomart

Category Protein
Source Mammalian Cells
Species Human

Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta - CSB-YP865102HU CSB-EP865102HU CSB-BP865102HU CSB-MP865102HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (PLCB1), partial, Recombinant Protein - MBS1464195 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Recombinant Phospholipase C Beta 1, Phosphoinositide Specific (PLCb1) - RPB596Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

PLCB1 (transcript variant 1) - TP310197 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
PLCB1

PLCB1 (transcript variant 2) - TP316150 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
PLCB1

PLC-beta 1 Recombinant Protein Antigen - NBP2-38220PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

PLC-beta 1 Recombinant Protein Antigen - NBP2-37966PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

PLCB1 Peptide, Human - M34GP11895H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

PLCB1 Recombinant Protein (OPCD06259) - OPCD06259 from Aviva Systems Biology

Category Protein
Source E.coli
Species Human
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