PLCB1

Gene Symbol PLCB1
Entrez Gene 23236
Alt Symbol EIEE12, PI-PLC, PLC-154, PLC-I, PLC154, PLCB1A, PLCB1B
Species Human
Gene Type protein-coding
Description phospholipase C, beta 1 (phosphoinositide-specific)
Other Description 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate|1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1|PLC-beta-1|inositoltrisphosphohydrolase|monophosphatidylinositol phosphodiesterase|phosphoinositidase C|phospholipase C-I|triphosphoinositide phosphodiesterase
Swissprots Q9NTH4 Q9H8H5 Q5TGC9 Q8IV93 Q17RQ6 Q9NQH9 Q9H4H2 Q9BQW2 Q9UJP6 D3DW12 O60325 Q5TFF7 Q9NQ65 D3DW13 Q9NQ66 Q9UM26
Accessions CBF62960 CBF74720 CBU87836 CBU96783 EAX10372 EAX10373 EAX10374 EAX10375 EAX10376 Q9NQ66 AB011153 BAA25507 AJ278313 CAB98142 AJ278314 CAB98143 AK023689 BAB14641 AK127693 BAG54550 AK299195 BAG61238 AK310597 AL137267 CAB70666 AY004175 AAF86613 BC069420 AAH69420 BC117231 AAI17232 BQ184058 HQ258537 ADR83291 XM_011529199 XP_011527501 XM_011529200 XP_011527502 XM_011529201 XP_011527503 XM_011529202 XP_011527504 XM_011529203 XP_011527505 NM_015192 NP_056007 NM_182734 NP_877398
Function The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Subcellular Location Nucleus membrane {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes. {ECO:0000250}.
Top Pathways Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway, Thyroid hormone synthesis, Estrogen signaling pathway, Inflammatory mediator regulation of TRP channels

PLC β1 siRNA (h) - sc-36266 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLC β1 shRNA Plasmid (h) - sc-36266-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLC β1 shRNA (h) Lentiviral Particles - sc-36266-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLC-beta 1 RNAi - H00023236-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU122681 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16920 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16920 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PLCB1 siRNA (Human) - CRH8111 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PLC-beta 1 RNAi - H00023236-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human PLCB1 (NM_015192.2) - SHH377108 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PLCB1(NM_182734.1) - SHR119880 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PLCB1(NM_015192.2) - SHR119898 from Creative biogene

Category siRNA
Species Reactivities Human

Human PLCB1 siRNA - orb268613 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PLCB1 shRNA Plasmid (Human) - CHH8111 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PLCB1 miRNA 3'UTR clone - MiUTR1H-07976 from Creative biogene

Species Reactivities Human

PLCB1 miRNA 3'UTR clone - MiUTR1H-07977 from Creative biogene

Species Reactivities Human
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