PCBP2

Gene Symbol	PCBP2
Entrez Gene	5094
Alt Symbol	HNRNPE2, HNRPE2, hnRNP-E2
Species	Human
Gene Type	protein-coding
Description	poly(rC) binding protein 2
Other Description	alpha-CP2|heterogeneous nuclear ribonucleoprotein E2|heterogenous nuclear ribonucleoprotein E2|hnRNP E2|poly(rC)-binding protein 2
Swissprots	I6L8F9 Q6PKG5 Q59HD4 Q15366 Q32Q82 B4DXP5 Q6IPF4 Q68Y55 F8VYL7 G3V0E8 A8K7X6
Accessions	CAD88579 CAD88580 CAJ42709 EAW96706 EAW96707 EAW96708 EAW96709 EAW96710 EAW96711 Q15366 AB188306 BAD36897 AB208825 BAD92062 AK023529 AK123458 AK130583 AK225357 AK292141 BAF84830 AK299210 BAG61249 AK302067 BAG63457 BC001155 AAH01155 BC035420 BC071942 AAH71942 BC107688 AAI07689 BE748080 BF509278 BM764315 BU844465 CX164318 X78136 CAA55015 NM_001098620 NP_001092090 NM_001128911 NP_001122383 NM_001128912 NP_001122384 NM_001128913 NP_001122385 NM_001128914 NP_001122386 NM_005016 NP_005007 NM_031989 NP_114366
Function	Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation. {ECO:0000269|PubMed:19881509}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:19029303}. Cytoplasm {ECO:0000269|PubMed:19029303}. Note=Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm.
Tissue Specificity	Detected in all tissues examined.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PCBP2-Over-expression-Lysate - LY13008a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

PCBP2-Over-expression-Lysate - LY12814a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

PCBP2 overexpression lysate - LY403134 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PCBP2 overexpression lysate - LY417574 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PCBP2 overexpression lysate - LY420644 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PCBP2 overexpression lysate - LY426031 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PCBP2 overexpression lysate - LY427015 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PCBP2 overexpression lysate - LY427016 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PCBP2 overexpression lysate - LY429233 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PCBP2 293 Cell Lysate - 402721 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

PCBP2 Overexpression Lysate (Native) - NBL1-14143 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PCBP2 Overexpression Lysate (Native) - NBP2-07800 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PCBP2 Over-expression Lysate Product - GWB-DF6DF0 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

PCBP2 Overexpression Lysate (Native) - NBP2-09812 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human PCBP2 Knockdown Stable Cell Line - CSC-DC011363 from Creative biogene Category Cell Line Species Human

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