PCBP2

Gene Symbol	PCBP2
Entrez Gene	5094
Alt Symbol	HNRNPE2, HNRPE2, hnRNP-E2
Species	Human
Gene Type	protein-coding
Description	poly(rC) binding protein 2
Other Description	alpha-CP2|heterogeneous nuclear ribonucleoprotein E2|heterogenous nuclear ribonucleoprotein E2|hnRNP E2|poly(rC)-binding protein 2
Swissprots	I6L8F9 Q6PKG5 Q59HD4 Q15366 Q32Q82 B4DXP5 Q6IPF4 Q68Y55 F8VYL7 G3V0E8 A8K7X6
Accessions	CAD88579 CAD88580 CAJ42709 EAW96706 EAW96707 EAW96708 EAW96709 EAW96710 EAW96711 Q15366 AB188306 BAD36897 AB208825 BAD92062 AK023529 AK123458 AK130583 AK225357 AK292141 BAF84830 AK299210 BAG61249 AK302067 BAG63457 BC001155 AAH01155 BC035420 BC071942 AAH71942 BC107688 AAI07689 BE748080 BF509278 BM764315 BU844465 CX164318 X78136 CAA55015 NM_001098620 NP_001092090 NM_001128911 NP_001122383 NM_001128912 NP_001122384 NM_001128913 NP_001122385 NM_001128914 NP_001122386 NM_005016 NP_005007 NM_031989 NP_114366
Function	Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation. {ECO:0000269|PubMed:19881509}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:19029303}. Cytoplasm {ECO:0000269|PubMed:19029303}. Note=Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm.
Tissue Specificity	Detected in all tissues examined.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PCBP2/hnRNP E2 full length protein - ab116820 from Abcam Category Protein Source Wheat germ Species Human

Human PCBP2/hnRNP E2 protein fragment - ab152593 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human PCBP2 Protein - H00005094-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human PCBP2 Protein - H00005094-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PCBP2-Antibody-C-term-Blocking-peptide - BP12231b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PCBP2 Blocking Peptide - 33R-4463 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PCBP2 Blocking Peptide - 33R-9591 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PCBP2 / hnRNP-E2 - H00005094-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PCBP2 / hnRNP-E2 - H00005094-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PCBP2 / hnRNP-E2 - H00005094-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PCBP2 / hnRNP-E2 - H00005094-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PCBP2 fusion protein - Ag7229 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

PCBP2 fusion protein - Ag7102 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human PCBP2 - PCBP2-29961TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human PCBP2, His-tagged - PCBP2-1548H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Poly(rC)-binding protein 2(PCBP2) - CSB-YP622995HU CSB-EP622995HU CSB-BP622995HU CSB-MP622995HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PCBP2 / hnRNP-E2 (transcript variant 1) - TP310035 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

PCBP2 / hnRNP-E2 (transcript variant 2) - TP300339 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

PCBP2 / hnRNP-E2 (transcript variant 3) - TP313289 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

PCBP2 / hnRNP-E2 (transcript variant 7) - TP325457 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

PCBP2 / hnRNP-E2 (transcript variant 6) - TP325491 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Poly (rC)-binding protein 2 (PCBP2), Recombinant Protein - MBS1430412 from MyBioSource Category Protein Prices $1,130.00, $1,130.00, $1,360.00, $1,360.00, $1,800.00, $1,800.00, $2,265.00, $2,265.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PCBP2 Protein - NBP1-83241PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

PCBP2 Peptide, Human - M34GP11363H from Creative Peptides Category Peptide Source Synthetic. Species Human

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