PCBP2

Gene Symbol PCBP2
Entrez Gene 5094
Alt Symbol HNRNPE2, HNRPE2, hnRNP-E2
Species Human
Gene Type protein-coding
Description poly(rC) binding protein 2
Other Description alpha-CP2|heterogeneous nuclear ribonucleoprotein E2|heterogenous nuclear ribonucleoprotein E2|hnRNP E2|poly(rC)-binding protein 2
Swissprots I6L8F9 Q6PKG5 Q59HD4 Q15366 Q32Q82 B4DXP5 Q6IPF4 Q68Y55 F8VYL7 G3V0E8 A8K7X6
Accessions CAD88579 CAD88580 CAJ42709 EAW96706 EAW96707 EAW96708 EAW96709 EAW96710 EAW96711 Q15366 AB188306 BAD36897 AB208825 BAD92062 AK023529 AK123458 AK130583 AK225357 AK292141 BAF84830 AK299210 BAG61249 AK302067 BAG63457 BC001155 AAH01155 BC035420 BC071942 AAH71942 BC107688 AAI07689 BE748080 BF509278 BM764315 BU844465 CX164318 X78136 CAA55015 NM_001098620 NP_001092090 NM_001128911 NP_001122383 NM_001128912 NP_001122384 NM_001128913 NP_001122385 NM_001128914 NP_001122386 NM_005016 NP_005007 NM_031989 NP_114366
Function Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation. {ECO:0000269|PubMed:19881509}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19029303}. Cytoplasm {ECO:0000269|PubMed:19029303}. Note=Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm.
Tissue Specificity Detected in all tissues examined.

hnRNP E2 (H-15) - sc-30725 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
hnRNP E2 (H-15): sc-30725. Western blot analysis of hnRNP E2 expression in Sol8 nuclear extract.

hnRNP E2 (A-14) - sc-30724 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
hnRNP E2 (A-14): sc-30724. Western blot analysis of hnRNP E2 expression in K-562 (A), Raji (B), Hep G2 (C), HeLa (D) and Jurkat (E) whole cell lysates.

hnRNP E2 (N-16) - sc-30723 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
hnRNP E2 (N-16): sc-30723. Western blot analysis of hnRNP E2 expression in Sol8 nuclear extract.

hnRNP E2 (P-20) - sc-16506 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

hnRNP E2 (23-G) - sc-101136 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
hnRNP E2 (23-G): sc-101136. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human testis tissue showing nuclear and cytoplasmic localization.

Anti-PCBP2/hnRNP E2 antibody - ab77323 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
ICC/IF image of ab77323 stained MCF7 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab77323, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96879, DyLight® 488 goat anti-mouse IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-PCBP2/hnRNP E2 antibody - ab154245 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PCBP2/hnRNP E2 antibody (ab154245) at 1/2000 dilutionLane 1 : Jurkat whole cell lysateLane 2 : Raji whole cell lysateLane 3 : K562 whole cell lysateLane 4 : NCI H929 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-PCBP2/hnRNP E2 antibody - ab95942 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-PCBP2/hnRNP E2 antibody (ab95942) at 1/500 dilution + HepG2 whole cell lysate at 30 µg

Anti-PCBP2/hnRNP E2 antibody [376CT13.1.2] - ab61334 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 376CT13.1.2
All lanes : Anti-PCBP2/hnRNP E2 antibody [376CT13.1.2] (ab61334) at 5 µg/mlLane 1 : K562 (Human erythromyeloblastoid leukemia cell line) Whole Cell LysateLane 2 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate Lane 3 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate Lane 4 : Raji (Human Burkitt's lymphoma cell line) Whole Cell Lysate Lysates/proteins at 20 µg per lane.SecondaryGoat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/5000 dilutionPerformed under reducing conditions.

Anti-PCBP2/hnRNP E2 antibody [5F12] - ab110200 from Abcam

Prices $464.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 5F12
Immunohistochemistry analysis of formalin fixed, paraffin embedded human testis tissue using ab110200 at 5 µg/ml.

Anti-PCBP2/hnRNP E2 antibody [EPR14858] - ab184962 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14858
All lanes : Anti-PCBP2/hnRNP E2 antibody [EPR14858] (ab184962) at 1/5000 dilutionLane 1 : HeLa cell lysateLane 2 : Raji cell lysateLane 3 : K562 cell lysateSecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-PCBP2/hnRNP E2 antibody [EPR14859(2)] - ab200835 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14859(2)
All lanes : Anti-PCBP2/hnRNP E2 antibody [EPR14859(2)] (ab200835) at 1/10000 dilutionLane 1 : HeLa (Human epithelial cells from cervix adenocarcinoma) whole cell lysateLane 2 : Jurkat (Human T cell leukemia cells from peripheral blood) whole cell lysateLane 3 : K562 (Human chronic myelogenous leukemia cells from bone marrow) whole cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-HNRNP-E2 / PCBP2 Antibody (clone 5F12) IHC-plus™ - LS-B4392 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 5F12
Anti-PCBP2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4392 concentration 5 ug/ml.

Anti-HNRNP-E2 / PCBP2 Antibody (aa1-363, Azide-free) - LS-C328164 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-HNRNP-E2 / PCBP2 Antibody - LS-C341429 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HNRNP-E2 / PCBP2 Antibody (aa31-80) - LS-C80352 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 2.5 ug/ml. Gel concentration: 12%.

Anti-HNRNP-E2 / PCBP2 Antibody (aa191-240) - LS-C31584 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
PCBP2 antibody LS-C31584 was used in IHC to stain formalin-fixed, paraffin-embedded human lung.

Anti-HNRNP-E2 / PCBP2 Antibody (aa302-365) - LS-C185979 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence of paraformaldehyde-fixed HeLa using PCBP2 antibody at 1:200 dilution.

Anti-HNRNP-E2 / PCBP2 Antibody (aa1-193) - LS-C186369 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence of methanol-fixed A431 using PCBP2 antibody at 1:200 dilution.

Anti-HNRNP-E2 / PCBP2 Antibody - LS-C332142 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human breast cancer using PCBP2 antibody at dilution of 1:200 (400x lens).

PCBP2 Antibody (5F12) - H00005094-M07 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5F12
Western Blot: PCBP2 Antibody (5F12) [H00005094-M07] - Analysis of PCBP2 expression in K-562 (Cat # L009V1).

PCBP2 Antibody - NBP2-19715 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PCBP2 Antibody [NBP2-19715] - Sample (30 ug of whole cell lysate) A: Jurkat B: Raji C: K562 D: NCI-H929 10% SDS PAGE gel, diluted at 1:2000.

PCBP2 Antibody - NBP1-57323 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PCBP2 Antibody [NBP1-57323] - Sample Tissue: Human Jurkat Antibody Dilution: 1.0 ug/ml

PCBP2 Antibody - NBP1-83241 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: PCBP2 Antibody [NBP1-83241] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.

PCBP2 Antibody - NBP1-31154 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PCBP2 Antibody [NBP1-31154] - Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE, antibody diluted at 1:500.
Search more