PTN

Gene Symbol PTN
Entrez Gene 5764
Alt Symbol HARP, HBGF8, HBNF, NEGF1
Species Human
Gene Type protein-coding
Description pleiotrophin
Other Description HB-GAM|HBBM|HBGF-8|HBNF-1|OSF-1|heparin affin regulatory protein|heparin binding growth factor 8|heparin-binding brain mitogen|heparin-binding growth factor 8|heparin-binding growth-associated molecule|heparin-binding neurite outgrowth-promoting factor 1|neurite growth-promoting factor 1|osteoblast-specific factor 1|pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)
Swissprots Q9UCC6 Q5U0B0 Q6ICQ5 P21246
Accessions AAB24425 AAB26456 EAL24052 EAW83869 EAW83870 EAW83871 EAW83872 P21246 AK290488 BAF83177 AK313424 BAG36216 AM392897 CAL37775 BC005916 AAH05916 BM968820 BT019692 AAV38498 CR450338 CAG29334 D90226 BAA14261 M57399 AAA35961 X52946 CAA37121 XM_005250515 XP_005250572 XM_005250516 XP_005250573 NM_002825 NP_002816
Function Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti- apoptotic signaling of PTN and regulation of cell proliferation. {ECO:0000269|PubMed:11278720, ECO:0000269|PubMed:1768439}.
Subcellular Location Secreted.
Tissue Specificity Osteoblast and brain.

PTN CRISPR/Cas9 KO Plasmid (h) - sc-416415 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTN HDR Plasmid (h) - sc-416415-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTN Double Nickase Plasmid (h) - sc-416415-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTN Double Nickase Plasmid (h2) - sc-416415-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTN CRISPR Activation Plasmid (h) - sc-416415-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTN CRISPR Activation Plasmid (h2) - sc-416415-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTN Lentiviral Activation Particles (h) - sc-416415-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTN Lentiviral Activation Particles (h2) - sc-416415-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTN siRNA (h) - sc-39713 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PTN shRNA Plasmid (h) - sc-39713-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PTN shRNA (h) Lentiviral Particles - sc-39713-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU027141 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17685 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17685 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PTN siRNA (Human) - CRH3895 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Pleiotrophin/PTN RNAi - H00005764-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human PTN (NM_002825.5) - SHH386292 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PTN(NM_002825.5) - SHR151338 from Creative biogene

Category siRNA
Species Reactivities Human

Human PTN siRNA - orb264397 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PTN shRNA Plasmid (Human) - CHH3895 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PTN miRNA 3'UTR clone - MiUTR1H-08438 from Creative biogene

Species Reactivities Human
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